FOCUS trial: results, potentialities and limits

Saba, Luca; Balestrieri, Antonella; Serra, Alessandra; Garau, R.; Politi, Carola; Lucatelli, Pierleone; Murgia, Alessandro; Suri, Jasjit S.; Mannelli, Lorenzo

doi:10.21037/atm.2019.06.37

Cited by 1 publication

(1 citation statement)

References 23 publications

(27 reference statements)

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“…Nonetheless, the present result may not be the final conclusion, and the therapeutic effect of SSRIs and SNRIs for PSD functional rehabilitation remains controversial. Consequently, the two big ongoing trials, assessment of Fluoxetine in Stroke recovery (participants are being recruited from Australia, New Zealand and Vietnam), and efficacy of fluoxetine, a randomized Controlled Trial in Stroke (participants are being recruited from Sweden) will provide further information regarding fluoxetine for stroke recovery[ 48 ]. In addition, a meta-analysis using individual participant data will be needed[ 47 ].…”

Section: Depressive Disorders After Strokementioning

confidence: 99%

Neuropsychiatric issues after stroke: Clinical significance and therapeutic implications

Zhang¹,

Xu²,

Liu³

et al. 2020

WJP

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A spectrum of neuropsychiatric disorders is a common complication from stroke. Neuropsychiatric disorders after stroke have negative effects on functional recovery, increasing the rate of mortality and disability of stroke survivors. Given the vital significance of maintaining physical and mental health in stroke patients, neuropsychiatric issues after stroke have raised concerns by clinicians and researchers. This mini-review focuses on the most common non-cognitive functional neuropsychiatric disorders seen after stroke, including depressive disorders, anxiety disorders, post-traumatic stress disorder, psychosis, and psychotic disorders. For each condition, the clinical performance, epidemiology, identification of the therapeutic implication, and strategies are reviewed and discussed; the main opinions and perspectives presented here are based on the latest controlled studies, meta-analysis, or updated systematic reviews. In the absence of data from controlled studies, consensus recommendations were provided accordingly.

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Section: Depressive Disorders After Strokementioning

confidence: 99%