This urgent need, as we point out in the manuscript title, stems from the fact that a regulatory gap widely exists in current quality standards and regulations on masks and respirators. By surveying the relevant ASTM, NOISH, EU, China, and ISO standards, as listed in the manuscript, we found no regulation or recommendation pertinent to this type of respirable hazard. Non-medical substitutes, such as face coverings, are also subject to such risks if made with improper household materials.There are numerous studies on assessing the filtration efficiency of masks, respirators, and recently, cloth