Focus on Multi-targeted Role of Curcumin: a Boon in Therapeutic Paradigm

Grover, Madhuri; Behl, Tapan; Sachdeva, Monika; Bungao, Simona; Aleya, Lotfi; Setia, Dhruv

doi:10.1007/s11356-021-12809-w

Cited by 9 publications

(6 citation statements)

References 157 publications

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“…Curcumin is an important active polyphenolic substance derived from turmeric, a plant of the ginger family [10]. e chemical structure of curcumin is shown in Figure 1.…”

Section: Introductionmentioning

confidence: 99%

A Novel Curcumin-Based Drug Powder Inhalation Medicine for Chronic Obstructive Pulmonary Disease

Shen

Jiang²,

Chen

et al. 2021

Bioinorganic Chemistry and Applications

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The dry powder inhaler is a new form of drug delivery that is widely used as an alternative to traditional drug delivery methods, addressing the shortcomings of traditional drug delivery methods and obtaining better therapeutic results. This mode of delivery is also one of the most rational ways to treat pulmonary diseases such as chronic obstructive pulmonary disease (COPD). Curcumin, a natural polyphenol, has been shown to be effective in the treatment of COPD. In this study, different concentrations of curcumin ethanol solution were spray dried with mannitol as a carrier to obtain dry powder particles with different particle size distribution for the preparation of curcumin dry powder inhaler. The solubility and physicochemical properties were further characterized by differential scanning calorimetry (DSC), X-ray diffraction (XRD), and scanning electron microscopy. The characterization results showed that the product obtained in the experiment had reasonable particle size distribution and excellent solubility properties, which were positive for the treatment of COPD or other pulmonary diseases.

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“…Curcumin is an important active polyphenolic substance derived from turmeric, a plant of the ginger family [10]. e chemical structure of curcumin is shown in Figure 1.…”

Section: Introductionmentioning

confidence: 99%

A Novel Curcumin-Based Drug Powder Inhalation Medicine for Chronic Obstructive Pulmonary Disease

Shen

Jiang²,

Chen

et al. 2021

Bioinorganic Chemistry and Applications

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“…In addition, the co-administration of curcumin with chemotherapeutic agents induces synergistic action to increase anti-cancer activity [ 152 , 153 , 154 , 155 ]. Studies have shown that any drug administered in combination with curcumin could improve the anti-cancer effect [ 155 , 156 , 157 , 158 , 159 ].…”

Section: Candidates For New Therapeutics: Approach With Knowledge Fro...mentioning

confidence: 99%

Therapeutics for Chemotherapy-Induced Peripheral Neuropathy: Approaches with Natural Compounds from Traditional Eastern Medicine

Chung

Kim

2022

Pharmaceutics

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Chemotherapy-induced peripheral neuropathy (CIPN) often develops in patients with cancer treated with commonly used anti-cancer drugs. The symptoms of CIPN can occur acutely during chemotherapy or emerge after cessation, and often accompany long-lasting intractable pain. This adverse side effect not only affects the quality of life but also limits the use of chemotherapy, leading to a reduction in the survival rate of patients with cancer. Currently, effective treatments for CIPN are limited, and various interventions are being applied by clinicians and patients because of the unmet clinical need. Potential approaches to ameliorate CIPN include traditional Eastern medicine-based methods. Medicinal substances from traditional Eastern medicine have well-established analgesic effects and are generally safe. Furthermore, many substances can also improve other comorbid symptoms in patients. This article aims to provide information regarding traditional Eastern medicine-based plant extracts and natural compounds for CIPN. In this regard, we briefly summarized the development, mechanisms, and changes in the nervous system related to CIPN, and reviewed the substances of traditional Eastern medicine that have been exploited to treat CIPN in preclinical and clinical settings.

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“…The films incorporated with ascorbic acid, with or without the leaf extract of M. oleifera L., successfully retarded the browning of pear samples ( Figure 3 ) [ 53 ]. Another example is curcumin, which has been shown to exhibit not only antimicrobial and antioxidant properties [ 54 , 55 , 56 , 57 , 58 ] but also the capacity to change colour in response to changes in pH [ 59 , 60 ]. Over the years, numerous antioxidant packaging films have been generated from the use of curcumin, with macromolecules such as k-carrageenan [ 61 ], gelatin [ 62 ], corn zein [ 63 ], chitosan [ 64 ], and tara gum [ 60 ] being adopted as the host matrices.…”

Section: Selection Of Antioxidant Agents To Be Incorporated Into Polymeric Filmsmentioning

confidence: 99%

Design of Polymeric Films for Antioxidant Active Food Packaging

Lai

2021

IJMS

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Antioxidant active food packaging can extend the shelf life of foods by retarding the rate of oxidation reactions of food components. Although significant advances in the design and development of polymeric packaging films loaded with antioxidants have been achieved over the last several decades, few of these films have successfully been translated from the laboratory to commercial applications. This article presents a snapshot of the latest advances in the design and applications of polymeric films for antioxidant active food packaging. It is hoped that this article will offer insights into the optimisation of the performance of polymeric films for food packaging purposes and will facilitate the translation of those polymeric films from the laboratory to commercial applications in the food industry.

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Focus on Multi-targeted Role of Curcumin: a Boon in Therapeutic Paradigm

Cited by 9 publications

References 157 publications

A Novel Curcumin-Based Drug Powder Inhalation Medicine for Chronic Obstructive Pulmonary Disease

A Novel Curcumin-Based Drug Powder Inhalation Medicine for Chronic Obstructive Pulmonary Disease

Therapeutics for Chemotherapy-Induced Peripheral Neuropathy: Approaches with Natural Compounds from Traditional Eastern Medicine

Design of Polymeric Films for Antioxidant Active Food Packaging

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