Focus of attention modulates the heartbeat evoked potential

Petzschner, Frederike H.; Weber, Lilian; Wellstein, Katharina V.; Paolini, Gina; Tri, Cao; Stephan, Klaas Enno

doi:10.1016/j.neuroimage.2018.11.037

Cited by 174 publications

(190 citation statements)

References 98 publications

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“…The modulating nature of attention on HEPs is consistent with previous research and with the interpretation of the HEP as a marker of precision-weighted prediction error of each individual heartbeat (García-Cordero et al, 2017;Montoya et al, 1993;Petzschner et al, 2019;Schandry et al, 1986;Villena-González et al, 2017;Yuan et al, 2007). Attention is proposed to modulate predictive mechanisms by enhancing the precision of attended prediction errors, relative to the precision of their priors (Ainley et al, 2016;Hohwy, 2012;Petzschner et al, 2019). Subsequently, attending to internal signals could enhance the precision of interoceptive prediction errors, resulting in their propagation up the predictive hierarchy to update models for more accurate future predictions regarding each heartbeat.…”

Section: Discussionsupporting

confidence: 88%

“…Consistent with the characterisation of the HEP as a neural correlate of precision-weighted interoceptive prediction error, many studies have reported attentional modulation of the amplitude of the HEP -for example, during tasks involving attending to heartbeat sensations relative to external stimuli (García-Cordero et al, 2017;Montoya, Schandry, & Müller, 1993;Petzschner et al, 2019;Schandry et al, 1986;Villena-González et al, 2017;Yuan, Yan, Xu, Han, & Yan, 2007).…”

mentioning

confidence: 68%

“…One potential method of investigating the neural basis of interoceptive predictive mechanisms is by analysing heart-evoked potentials (HEPs) (Pollatos & Schandry, 2004;Schandry, Sparrer, & Weitkunat, 1986). HEPs are averaged electrophysiological signals timelocked to heartbeats and are thought to reflect neuronal processing of cardiac afferents, encompassing interoceptive prediction error of each individual heartbeat (Ainley, Apps, Fotopoulou, & Tsakiris, 2016;Petzschner et al, 2019). In a recent study on interoceptive predictions, Pfeiffer & De Lucia (2017) presented healthy participants with a sequence of tones that were either synchronous or asynchronous with their own heartbeat.…”

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confidence: 99%

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Skipping a beat: heartbeat-evoked potentials reflect predictions during interoceptive-exteroceptive integration

Banellis

Cruse

2020

Preprint

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Several theories propose that emotions and self-awareness arise from the integration of internal and external signals and their respective precision-weighted expectations.Supporting these mechanisms, research indicates that the brain uses temporal cues from cardiac signals to predict auditory stimuli, and that these predictions and their prediction errors can be observed in the scalp heartbeat-evoked potential (HEP). We investigated the effect of precision modulations on these cross-modal predictive mechanisms, via attention and interoceptive ability. We presented auditory sequences at short (perceived synchronous) or long (perceived asynchronous) cardio-audio delays, with half of the trials including an omission. Participants attended to the cardio-audio synchronicity of the tones (internal attention) or the auditory stimuli alone (external attention). Comparing HEPs during omissions allowed for the observation of pure predictive signals, without contaminating auditory input.We observed an early effect of cardio-audio delay, reflecting a difference in heartbeat-driven expectations. We also observed a larger positivity to omissions of sounds perceived as synchronous than to omissions of sounds perceived as asynchronous when attending internally only, consistent with the role of attentional precision for enhancing predictions.These results provide support for attentionally-modulated cross-modal predictive coding, and suggest a potential tool for investigating its role in emotion and self-awareness.

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Section: Discussionsupporting

confidence: 88%

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confidence: 68%

mentioning

confidence: 99%

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Skipping a beat: heartbeat-evoked potentials reflect predictions during interoceptive-exteroceptive integration

Banellis

Cruse

2020

Preprint

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“…Similar modulation of early SEP components (P50) has previously been shown along with shifts of spatial attention (Forschack et al, 2017;Schubert et al, 2008). Given that HEP amplitude has been found to be significantly higher during interoceptive compared to exteroceptive attention (García-Cordero et al, 2017;Petzschner et al, 2019;Villena-González et al, 2017), we propose that the modulations of HEP amplitude reflect attentional shifts between external stimuli (exteroception) and internal bodily states (interoception). In line with this view, it has been suggested that the sudden ''ignition'' of a spontaneous internal activity can block external sensory processing (Dehaene & Changeux, 2005).…”

supporting

confidence: 78%

Heart-Brain Interactions Shape Somatosensory Perception and Evoked Potentials

Iliopoulos

Forschack

et al. 2019

Preprint

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ABSTRACTHuman perception either refers to the external world, exteroception, or internal body parts such as the heart, interoception. How these two types of perception interact is poorly understood. Using electroencephalography, we identify two heartbeat-related modulations of conscious somatosensory perception: (i) When stimulus timing coincided with systole of the cardiac cycle, participants were less likely to detect and localize somatosensory stimuli, and late components (P300) of the somatosensory-evoked potential (SEP) were attenuated. (ii) The amplitude of the heartbeat-evoked potential (HEP) negatively correlated with detection bias (criterion) and localization accuracy. Furthermore, higher HEP amplitudes were followed by decreases in both early and late SEP amplitudes. Both heartbeat-related effects were independent of the alpha oscillations’ influence on somatosensory processing. We conclude that internal signals are integrated into our conscious perception of the world, and connect our results to predictive processing (heartbeat-coupled stimulus timing) and attentional shifts between exteroception and interoception (HEP amplitude).

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“…Methods to induce controlled perturbations of interoception have so far been trialled in the cardiac domain (via intra-venous administration of isoproterenol 13 ), with breathing (via inspiratory and/or expiratory resistance 12,14-17 ), with gastric and bladder disturbances (via inflation of inserted balloons 18 , or via baroreceptor manipulation 19 ). While pharmacologicallyinduced cardiac alterations induce strong effects and appeal to the wide body of research on natural fluctuations in interoceptive heart-related signals [20][21][22][23][24][25] , the time-related decays required for returning to baseline as well as the burden and risks associated with repeated pharmacological interventions within the same subject pose restrictions on widespread application of this method. Similarly, the use of both gastric/bladder balloons and baroreceptor manipulations face challenges with regard to patient comfort and acceptance.…”

Section: Introductionmentioning

confidence: 99%

Tools and Resources: Remote, automated and MRI-compatible administration of interoceptive inspiratory resistive loading

2019

Preprint

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Research on how humans perceive sensory inputs from their bodies ('interoception') has been rapidly gaining momentum, with interest across a host of disciplines from physiology through to psychiatry. However, studying interoceptive processes is not without significant challenges, and many methods utilised to access internal states have been largely devoted to capturing and relating naturally-occurring variations in interoceptive signals (such as heartbeats) to measures of how the brain processes these signals. An alternative procedure involves the controlled perturbation of specific interoceptive axes. This is challenging because it requires non-invasive interventions that can be repeated many times within a subject and that are potent but safe.Here we present an effective methodology for instigating these perturbations within the breathing domain. We describe a custom-built circuitry that is capable of delivering inspiratory resistive loads automatically and precisely. Importantly, our approach is compatible with magnetic resonance imaging environments, allowing for the administration of complicated experimental designs in neuroimaging as increasingly required within developing fields such as computational psychiatry/psychosomatics. We describe the experimental setup for both the control and monitoring of the inspiratory resistive loads, and demonstrate its possible utilities within different study designs. This methodology represents an important step forward from the previously utilised, manually-controlled resistive loading setups, which present significant experimental burdens with prolonged and/or complicated sequences of breathing stimuli.

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Focus of attention modulates the heartbeat evoked potential

Cited by 174 publications

References 98 publications

Skipping a beat: heartbeat-evoked potentials reflect predictions during interoceptive-exteroceptive integration

Skipping a beat: heartbeat-evoked potentials reflect predictions during interoceptive-exteroceptive integration

Heart-Brain Interactions Shape Somatosensory Perception and Evoked Potentials

Tools and Resources: Remote, automated and MRI-compatible administration of interoceptive inspiratory resistive loading

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