Focus Issue: Neck Dissection for Oropharyngeal Squamous Cell Carcinoma

Abel, Kathryn M. Van; Moore, Eric J.

doi:10.5402/2012/547017

Cited by 14 publications

(16 citation statements)

References 67 publications

(133 reference statements)

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“…Therefore, the gold standard for determining the ''N stage'' is based on pathologic evaluation of nodal tissue [21]. Distant metastasis at presentation are rare (2-5 %) [22,23], and most commonly involve the lung, liver and bone [24].…”

Section: Diagnosismentioning

confidence: 99%

Surgical Management of Oropharyngeal Squamous Cell Carcinoma

Abel

Moore

2013

Curr Otorhinolaryngol Rep

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Squamous cell carcinoma of the oropharynx (OPSCC) occurs with an age-adjusted incidence rate of 2.2/ 100,000 per year, and makes up one of the largest growing subsets of head and neck cancer. Traditional risk factors include alcohol and tobacco exposure, however, the demographics have changed significantly over the past 2-3 decades, with human papillomavirus (HPV) infection now considered one of the most important risk factors. As our understanding of HPV-related OPSCC has developed, there has been increasing evidence that this new tumor subtype has a better overall prognosis and response to therapies. This review focuses on OPSCC from a surgical perspective. We review the relevant anatomy, diagnosis and workup, and discuss several different surgical approaches for management of this disease, including transoral robotic surgery, lateral oropharyngectomy and tonsillectomy, base of tongue resection, and neck dissection. In addition, the common complications associated with these treatment options are discussed.

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Section: Diagnosismentioning

confidence: 99%

Surgical Management of Oropharyngeal Squamous Cell Carcinoma

Abel

Moore

2013

Curr Otorhinolaryngol Rep

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“…1,2 The rate of clinically detectable LN metastasis in oropharyngeal SCC (OPSCC) ranges from 40% to >80%, and the rate of occult LN metastasis approaches 30%. [3][4][5][6][7] Most head and neck oncologists agree that a patient with a predicted rate of occult LN metastasis >15% to 20% should have either surgery or radiotherapy, rather than observation. 8 Surgical treatment of neck metastasis has evolved to provide oncologic efficacy while minimizing treatment-associated morbidity.…”

Section: Introductionmentioning

confidence: 99%

Level IIB lymph node metastasis in oropharyngeal squamous cell carcinoma

et al. 2013

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This study uniquely demonstrated a statistically significant association between clinical tumor stage and tonsil subsite with level IIB metastasis in OPSCC. Considering the predicted incidence of nodal metastasis, we conclude that level IIB neck dissection can be omitted in early stage (T1 or T2) clinically node negative (cN0) OPSCC. In patients with a cN0 neck and advanced OPSCC (T3 or T4), primary tumor in the tonsil, or ipsilateral clinically node positive (cN(+) ) and contralateral cN0 neck, level IIB dissection should be considered. Level IIB dissection should be performed routinely in patients with cN(+) OPSCC.

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“…trostomy. The tonsillar node in the subdigastric group is the first one involved in tonsillar fossa cancer 55 . If there is no clinical evidence of cervical lymph node involvement, a selective neck dissection should be performed.…”

Section: Oropharyngeal (Tonsillar) Cancermentioning

confidence: 99%

Difficulties in the surgical management of head and neck cancer patient

Sarafoleanu

Vuzitas

Manea

2017

Romanian Journal of Rhinology

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Malignancies of the upper aerodigestive tract are high morbidity bearing and life-threatening diseases, which require thorough care from diagnostic suspicion and confirmation to surgical and/or oncologic treatment and rehabilitation. Difficulties in managing head and neck cancers arise from delays in diagnosis and treatment caused by either patient-related factors or healthcare system-related factors. Tumor origin and stage determine whether surgical excision is feasible, the approach required for safe excision, the extent of functional and aesthetic sacrifice required to attain oncologic safety and the need for reconstructive surgery. A thorough and systematic preoperative risk versus benefits assessment to select potential surgical candidates and give realistic outcomes is important from both a medical and a legal point of view. Because tumors in the head and neck region frequently involve more than one system and sensory organ, potential loss of function from either the disease course, surgical or nonsurgical treatment should be taken into account form a quality of life perspective. Effective management of head and neck cancer patients requires the cooperation and combined effort of a multidisciplinary team of surgeons, physicians and other workers over a long period of time which, in the absence of a specialised head and neck cancer centre and guidelines, can lead to increased morbidity and mortality, and patient dissatisfaction.

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Focus Issue: Neck Dissection for Oropharyngeal Squamous Cell Carcinoma

Cited by 14 publications

References 67 publications

Surgical Management of Oropharyngeal Squamous Cell Carcinoma

Surgical Management of Oropharyngeal Squamous Cell Carcinoma

Level IIB lymph node metastasis in oropharyngeal squamous cell carcinoma

Difficulties in the surgical management of head and neck cancer patient

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