Focal liver lesions other than hepatocellular carcinoma in cirrhosis: Diagnostic challenges

Möller, Kathleen; Zadeh, Ehsan Safai; Görg, Christian; Ye, Dong; Cui, Xin-Wu; Lim, Adrian; Molo, Chiara De; Serra, Carla; Algíbez, Ana Martín; Berzigotti, Analisa; Piscaglia, Fabio; Faiss, Siegbert; Dietrich, Christoph F.

doi:10.2478/jtim-2022-0068

Cited by 14 publications

(10 citation statements)

References 109 publications

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“…Penyebab sirosis sangat bervariasi di setiap negara (Mittal et al, 2016). Sirosis hati dikaitkan dengan nodul regeneratif dan peningkatan risiko pengembangan karsinoma hepatoseluler (HCC) (Möller et al, 2022). Karsinoma hepatoseluler adalah bentuk paling umum dari kanker hati.…”

Section: Pendahuluanunclassified

Antitumor from Several Plant Compounds Against Hepatocellular Carcinoma Cell Line Hep3B: Mini Systematic Review

Aini,

Zikrah,

Safril

et al. 2023

JBT

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Liver cancer is a global health challenge, with more than one million cases expected by 2025. Hepatocellular carcinoma (HCC) is the most common form of liver cancer and accounts for approximately 90% of cases. Nature provides a large source of natural medicines and compounds, one of which is plants. So, this article is made to contain information on the potential of several plants as antitumor agents. The method of preparing articles through literature review studies that collect articles from various sources such as ScienceDirect, google scholar, PubMed and others in the range of 2013 to 2023. There are ten plant bioactive compounds that have been tested in vitro on Hep3B cell lines to see their toxicity. These plant bioactive compounds play an important role in the proliferation phase, cell cycle, and cell apoptosis in liver cancer and have potential as antitumor.

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Section: Pendahuluanunclassified

Antitumor from Several Plant Compounds Against Hepatocellular Carcinoma Cell Line Hep3B: Mini Systematic Review

Aini,

Zikrah,

Safril

et al. 2023

JBT

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“…sarcoidosis [20][21][22][23], tuberculosis [24,25], hydatid cysts [26][27][28][29], alveolar echinococcosis [27], schistosomiasis [30,31], ascariasis [32,33], fasciolosis [34], clonorchis and opisthorchis [35], toxocariasis [36], bacillary angiomatosis [37], and amyloidosis with spontaneous hemorrhage [38], as well as rare FLLs in pediatric patients [39,40]. More recently rare bacterial [41], parasitic [42], and autoimmune focal liver lesions [43], bile duct lesions [44], other benign FLL [45,46], and FLL other than HCC in the cirrhotic liver [47,48] have been featured as well [41][42][43]49].…”

Section: Introductionmentioning

confidence: 99%

Comments on and illustrations of the WFUMB CEUS liver guidelines: Rare malignant neuroendocrine and predominant epithelioid liver lesions

Zadeh,

Huber,

Görg

et al. 2024

Med Ultrason

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The diagnosis or rare, non-hematologic malignant lesions of the liver may be a challenge owing to the rarity of the disease, and is usually made by histological confirmation. Ultrasound with color Doppler and contrast-enhanced, if required, taking into account the clinical background of the patient, may help to focus the differential diagnosis. In this review, we describe the pathological and ultrasound features of rare malignant neuroendocrine and predominantly epithelioid liver lesions including primary neuroendocrine tumor of the liver, Invasive mucinous cystic neoplasm of the liver, and also hepatoblastoma.

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“…Liver cancer resection, especially in patients with hemihepatectomy or extended hemihepatectomy, often leads to poor prognosis, such as liver insufficiency and even liver failure and death, because the standard residual liver volume (SRLV) cannot be fully compensated after surgery[ 10 ]. Research suggests that preoperative liver fibrosis and cirrhosis are the main causes[ 11 ]. In recent years, an increasing number of studies have shown that the liver stiffness measure (LSM) value is significantly related to the degree of cirrhosis, which can reflect the degree of liver inflammation and fibrosis[ 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

Clinical study of standard residual liver volume and transient elastography in predicting poor prognosis of patients after hemihepatectomy

Yue,

Zhang,

Yan

et al. 2023

World J Clin Oncol

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BACKGROUND Liver cancer resection, especially in patients with hemihepatectomy or extended hemihepatectomy, often leads to poor prognosis, such as liver insufficiency and even liver failure and death, because the standard residual liver volume (SRLV) cannot be fully compensated after surgery. AIM To explore the risk factors of poor prognosis after hemihepatectomy for hepatocellular carcinoma and evaluate the application value of related prognostic approaches. METHODS The clinical data of 35 patients with primary liver cancer in Nantong Third People's Hospital from February 2016 to July 2020 were retrospectively analyzed. The receiver operating characteristic curve was created using medcac19.0.4 to compare the critical values of the SRLV in different stages of liver fibrosis after hemihepatectomy with those of liver dysfunction after hemihepatectomy. It was constructed by combining the Child-Pugh score to evaluate its application value in predicting liver function compensation. RESULTS The liver stiffness measure (LSM) value and SRLV were associated with liver dysfunction after hemihepatectomy. Logistic regression analysis showed that an LSM value ≥ 25 kPa [odds ratio (OR) = 6.254, P < 0.05] and SRLV ≤ 0.290 L/m2 (OR = 5.686, P < 0.05) were independent risk factors for postoperative liver dysfunction. The accuracy of the new liver reserve evaluation model for predicting postoperative liver function was higher than that of the Child-Pugh score (P < 0.05). CONCLUSION SRLV and LSM values can be used to evaluate the safety of hemihepatectomy. The new liver reserve evaluation model has good application potential in the evaluation of liver reserve function after hemihepatectomy.

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Focal liver lesions other than hepatocellular carcinoma in cirrhosis: Diagnostic challenges

Cited by 14 publications

References 109 publications

Antitumor from Several Plant Compounds Against Hepatocellular Carcinoma Cell Line Hep3B: Mini Systematic Review

Antitumor from Several Plant Compounds Against Hepatocellular Carcinoma Cell Line Hep3B: Mini Systematic Review

Comments on and illustrations of the WFUMB CEUS liver guidelines: Rare malignant neuroendocrine and predominant epithelioid liver lesions

Clinical study of standard residual liver volume and transient elastography in predicting poor prognosis of patients after hemihepatectomy

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