“…Although the etiology of DH is unclear, both mechanical 13,23 and vascular theories 24,25 having been hypothesized, these results suggest that a localized structural LC defect might be a factor predisposing to the disruption of the microvascular structure passing through the damaged sector. Focal LC defects occur mostly on the far periphery of the LC at or near the laminar insertion point, 21,26 and similarly, DH occurs preferentially at the disc margin. 1,27 In the same context, several studies have demonstrated that, in glaucomatous eyes, FLCD is spatially correlated not only with neuroretinal rim loss, 26 visual field defects, 21 and RNFL defects, 28 but also with DH.…”