Focal epithelial hyperplasia of the oral mucosa.

Starink, Th. M.; Woerdeman, M.J.

doi:10.1111/j.1365-2133.1977.tb07131.x

Cited by 18 publications

(3 citation statements)

References 15 publications

(13 reference statements)

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“…Other reports have since appeared and it is now clear that the disease occurs in certain native ethnic groups such as Blacks, Esquimos, South American Indians and rarely in caucasians (12,14). The disease occurs primarily in groups with a poor social and economic status and affects mainly children and young adults with frequent manifestation within the same family.…”

Section: Discussionmentioning

confidence: 97%

Human papillomavirus type 13 DNA in focal epithelial hyperplasia among Mexicans

Hernández-Jáuregui

Eriksson²,

Pérez

et al. 1987

Archives of Virology

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Human papillomavirus (HPV) type 13 DNA was detected in focal epithelial hyperplasia lesions of the oral mucosa in seven half-caste mexicans. The lesions contained intracellular papillomavirus-like particles with a diameter of about 50 nm. DNA extracted from biopsies contained unintegrated HPV type 13 DNA genomes as revealed by Southern blot hybridization. The HPV 13 DNA that was isolated in the present study had the same restriction enzyme cleavage map as HPV 13 DNA, previously described by others. It was moreover confirmed that HPV type 13 genome is related to the genomes of HPV types 6 and 11.

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Section: Discussionmentioning

confidence: 97%

Human papillomavirus type 13 DNA in focal epithelial hyperplasia among Mexicans

Hernández-Jáuregui

Eriksson²,

Pérez

et al. 1987

Archives of Virology

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“…Multiple, symptomless, papillomatous-like swellings was found on the lower and upper lips, buccal mucosa, gingiva and the borders of the tongue of a 12-year-old black boy, the hard palate was involved as well. Two years later, Starink TM et al reported two MEH cases involving gingiva of a 9-year-old girl and a 4-year-old boy, respectively [ 12 ]. In 1982, Lutzner M et al described MEH lesions on the gingiva of a 10-year-old boy [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

Multifocal epithelial hyperplasia confined to the interdental papilla of an adult Chinese man: a rare case report and literature review

Wang,

Xu,

et al. 2023

BMC Oral Health

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Background Multifocal epithelial hyperplasia (MEH), or focal epithelial hypertension (FEH), or Heck’s disease, is an uncommon, benign oral mucosal disease associated with human papillomavirus infection. It is mostly observed in indigenous populations of the world, and has been rarely reported in China. However, previous research suggested there might be a greater prevalence of MEH in the Chinese population. While predominantly involves the lips, buccal mucosa and tongue, MEH was occasionally reported to affect the hard palate and gingiva as well. Case presentation This paper reports a case of extensive MEH lesions that confined to the interdental papilla of a Chinese male without detection of HPV, and summarizes the published gingiva-involved MEH reports from 1966 until present. The lesions were excised with an Er: YAG laser after scaling and root planning, no recurrence was observed after 6-month follow-up. Conclusions The present report illustrates the need for clinicians to be aware of rare presentations of MEH to facilitate a prompt diagnosis and proper management. More reports are encouraged to determine a correct prevalence rate of MEH in China.

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“…The etiology has not been determined; a virus (Praetorius-Clausen & Willis 1971, Hanks et al 1972, van Wyk et al 1977 and heredity (Gomez et al 1969, Schock 1969, Buchner 1978 have been suggested as etiologic factors. While viral particles of the papova virus group have been demonstrated in some human cases (Hanks et al 1972, Praetorius-Clausen 1972, van Wyk et al 1977, not all investigators have been able to demonstrate them (Orfanos et al 1974, 03OO-9777/79/040213-ll$02.50/0 Buchner et al 1975, Starink & Woerdeman 1977. Viral particles have also been demonstrated in chimpanzee lesions (Hollander & van Noord 1972, Tate et al 1973).…”

Section: Focalmentioning

confidence: 99%

Focal epithelial hyperplasia in rabbit oral mucosa

Chen¹

1979

J Oral Pathology Medicine

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Several papules on the floor of the mouth and the ventral surface of the tongue of a zincdeficient rabbit were studied by light and electron microscopy. These papules appeared to be consistent with focal epithelial hyperplasia of man and chimpanzee. There was a concurrence of cytoplasmic vacuolization with the appearance of viral particles within the nucleus. Intranuclear crystalline viral aggregates were frequently observed in the upper spinous cells.

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Focal epithelial hyperplasia of the oral mucosa.

Abstract: Two negro siblings with focal epithelial hyperplasia of the oral mucosa are described. A review of the literature is presented.

Cited by 18 publications

References 15 publications

Human papillomavirus type 13 DNA in focal epithelial hyperplasia among Mexicans

Human papillomavirus type 13 DNA in focal epithelial hyperplasia among Mexicans

Multifocal epithelial hyperplasia confined to the interdental papilla of an adult Chinese man: a rare case report and literature review

Focal epithelial hyperplasia in rabbit oral mucosa

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