Focal differences in lipid metabolism of the young pig aorta

Somer, John B.; Schwartz, Colin J.

doi:10.1016/0014-4800(76)90001-0

Cited by 12 publications

(1 citation statement)

References 48 publications

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“…A estimulação da síntese de novo de ácidos graxos pela insulina no tecido adiposo suíno, in vitro e in vivo, já foi documentada por muitos autores (BUDD et al, 1994;MILLS, 1999;SOMER et al, 1976;SOMER;SCHWARTZ, 1976;WALTON;EHTERTON, 1986). A insulina estimula a lipogênese aumentando a captação de glicose pelo adipócito, via recrutamento de transportadores de glicose para a membrana plasmática, e ativando enzimas glicolíticas e lipogênicas, por meio de modificações covalentes.…”

Section: Regulação Pela Insulinaunclassified

Metabolism of glycerol in pigs fed diets containing mixed crude glycerin and β-adrenergic agonist

et al. 2019

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The optimised use of mixed crude glycerin (MCG) and ractopamine hydrochloride (RH) in diets for finishing pigs requires a better understanding of glycerol metabolism. Therefore, the present study evaluated the performance, blood parameters, metabolite concentrations in the Longissimus lumborum muscle and the activity of enzymes in the liver, subcutaneous adipose tissue and kidney of pigs fed diets containing MCG and/or RH. According to the initial weight, 64 barrows were distributed in a 4 × 2 factorial design, corresponding to four concentrations of MCG (0, 100, 150, and 200 g/kg) in diets containing 0 or 10 mg/kg of RH. There was no MCG × RH interaction for any of the evaluated parameters (P > 0.05). Moreover, there was no isolated effect of dietary MCG or RH on the weight gain and the blood concentrations of glucose, insulin, triacylglycerols, total cholesterol, total protein, albumin, creatinine, cortisol and lactate (P > 0.05). There was a higher rate of phosphorylation of glycerol in the liver, stimulation of lipogenesis in adipose tissue and a likely increase in the utilisation of glycerol by muscle fibres in response to an increased concentration of circulating glycerol from the diet (P < 0.05). In contrast, when the diet contained up to 200 g/kg MCG and 10 mg/kg RH, there were indications of a lower utilisation of glycerol for the synthesis of triacylglycerols in muscle, liver and adipose tissue, in addition to increased oxidation of amino acids in the liver followed by improved feed conversion of pigs (P < 0.05).

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