Focal Central Nervous System Abnormalities in Patients with Misidentification Syndromes

Bilateral Anterior Cortical Atrophy and Subcortical Atrophy in Reduplicative Paramnesia: A Case-Control Study of Computed Tomography in 10 Patients

“…Previous case-control studies of CT in OMS patients have consistently found vermis and brain-stem atrophy, as has this one (3,7,9).…”

“…Degrees of atrophy were defmed according to the following rating scores: 0 = normal appearance with narrow sulci and cerebrospinal fluid (CSF) spaces and wide gyri; 1 = mild atrophy with prominent sulci and CSF spaces or atrophic gyri;2= moderate atrophy with very enlarged sulci and CSF spacesor very atrophic gyri; and 3 = severe atrophy with severely enlarged sulci and CSF spaces or severely atrophic gyri. This method of visual assessment has been found to be useful in other published studies (3,(7)(8)(9) and is very similar to at least 1 other assessment and rating method that has also been well accepted in the literature (10). This technique is no longer considered state-of-the-art because of the advent of computerized assessment tools that can automatically provide quantitative volumetric analysis for CT imaging.…”

“…The bulk of the small literature on RP, however, comprises case reports, usually describing neurologic and not psychiatric patients. It is therefore not possible to conclude whether our series is (3,7,9,13). Here the clinical characteristics are similar, and it is likely that our series ofpatients is representative ofpsychiatric inpatients with RP.…”

Clonal pluralization, as an interpretative delusion after a hallucinatory form of autoscopy

“…Referring to the debates around the classical dichotomy of psychiatric literature dealing with Capgras symptom and DMSs, and the neurological literature dealing mainly with reduplicative paramnesia 17 numerous studies witness growing evidence of organic background in different misidentification syndromes 3,[18][19][20] . Nevertheless, some of them underline that no single brain lesion is specifically associated with reduplications 21 .…”

Face Processing Impairments and Delusional Misidentification

“…This emphasis, however, has lessened somewhat because of the mounting evidence of organic involvement (usually in the form of clearly demonstrable brain lesions) in all types of delusional misidentification (Joseph, 1986), 0953-4180/90/030153+ 16 $3.50/0 including Capgras' delusion (e.g. Weston and Whitlock, 1971;MacCallum, 1973MacCallum, , 1985Luaute et at., 1978;Alexander et at., 1979;Wilcox and Waziri, 1983;Lewis, 1987), the Fregoli delusion (de Pauw et at., 1987;Joseph and O'Leary, 1987), and intermetamorphosis (Bick, 1986;Joseph, 1987).…”