Focal and multifocal osteosarcoma in two foals

Livesey, M. A.; Wilkie, Ian

doi:10.1111/j.2042-3306.1986.tb03668.x

Cited by 38 publications

(43 citation statements)

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“…2,3 Trauma as a predisposing factor is supported by the fact that the majority of osteosarcomas in humans and small animals occur within weight-bearing bones such as the proximal humerus, distal radius, distal femur, and proximal tibia. 2,3 It is postulated that osteosarcomas occur in the mandible of large animal species because of the trauma associated with persistent chewing. 3 This report documents a series of 8 cases of equine osteosarcoma ( Table 1).…”

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confidence: 98%

“…2,3 It is postulated that osteosarcomas occur in the mandible of large animal species because of the trauma associated with persistent chewing. 3 This report documents a series of 8 cases of equine osteosarcoma ( Table 1).…”

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confidence: 99%

“…4 In horses, osteosarcoma is a rare tumor, with the majority of cases occurring in the head, and, more specifically, in the mandible of young horses, with few case reports documenting osteosarcoma within the appendicular skeleton and vertebral column. [2][3][4][5] Osteosarcomas within the maxilla and mandible cause pronounced disruption of the face and dental arcade and interference with normal mastication. 1 The etiology and pathogenesis of osteosarcomas is unknown, although trauma, viral infection, exposure to radiation, and genetic factors have been hypothesized as predisposing factors.…”

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Equine Osteosarcoma: A Series of 8 Cases

2007

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Abstract. In horses, osteosarcoma is a rare tumor, with the majority of reported cases occurring in the head, and, more specifically, in the mandible of young horses. The following report documents 8 cases of equine osteosarcoma, the majority occurring in male horses aged 7 years or older with a lack of metastasis identified in any horse. Six arose in the maxilla or mandible and one in the proximal tibia. The predominant subtype was fibroblastic osteosarcoma with fewer osteoblastic type tumors. All had osteoid and most had a chondromucinous matrix. Surgical excision was attempted in the majority of cases. An inability to completely excise the tumor and progressive disease typically resulted in euthanasia. To the authors' knowledge, this case series also documents the first report of an equine extraosseous osteosarcoma within the subcutaneous tissue caudal to the shoulder. Surgical excision appears successful with no recurrence of disease 14 months later. Further investigations of equine osteosarcoma and various chemotherapeutic agents are warranted to present additional treatment options.

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Equine Osteosarcoma: A Series of 8 Cases

2007

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“…The present report describes the clinical presentation, diagnostic findings, treatment and long‐term outcome in an English Cocker Spaniel with axial MOS that exhibited an unusual slow disease progression despite the advanced stage at diagnosis. Multicentric osteosarcoma is a rare presentation of OS in animals, and although described in the horse there has yet to be a published report of axial MOS in the dog . Osteosarcoma in dogs is the most common bone neoplasia in dogs and the appendicular presentation accounts for 75% of cases.…”

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Axial Multicentric Osteosarcoma in an English Cocker Spaniel

Parzefall

Decker

Carvalho

et al. 2016

Veterinary Internal Medicne

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“…While osteosarcomas are rarely reported in the horse, most of those recorded have been located in the region of the head (Thorp and Graham ; Barber et al . ; Livesey and Wilkie ; Bush et al . ).…”

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