fMRI of the Sensorimotor System

Filippi, Massimo; Messina, Roberta; Rocca, Maria A.

doi:10.1007/978-1-4939-5611-1_17

Cited by 2 publications

(3 citation statements)

References 167 publications

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“…Sensorimotor processing engages cortical and subcortical areas. The extensive sensorimotor investigations implicate the motor cortex of the frontal lobe, the sensory cortex of the parietal lobe, and the cerebellum ( Grodd et al, 2001 ; Hermes et al, 2012 ; Siero et al, 2014 ; Filippi et al, 2016 ). The sensorimotor pathway also engages the thalamus ( Mo and Sherman, 2019 ).…”

Section: Introductionmentioning

confidence: 99%

Functional mapping of sensorimotor activation in the human thalamus at 9.4 Tesla

et al. 2023

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Although the thalamus is perceived as a passive relay station for almost all sensory signals, the function of individual thalamic nuclei remains unresolved. In the present study, we aimed to identify the sensorimotor nuclei of the thalamus in humans using task-based fMRI at a field strength of 9.4T by assessing the individual subject-specific sensorimotor BOLD response during a combined active motor (finger-tapping) and passive sensory (tactile-finger) stimulation. We demonstrate that both tasks increase BOLD signal response in the lateral nuclei group (VPL, VA, VLa, and VLp), and in the pulvinar nuclei group (PuA, PuM, and PuL). Finger-tapping stimuli evokes a stronger BOLD response compared to the tactile stimuli, and additionally engages the intralaminar nuclei group (CM and Pf). In addition, our results demonstrate reproducible thalamic nuclei activation during motor and tactile stimuli. This work provides important insight into understanding the function of individual thalamic nuclei in processing various input signals and corroborates the benefits of using ultra-high-field MR scanners for functional imaging of fine-scale deeply located brain structures.

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Section: Introductionmentioning

confidence: 99%

Functional mapping of sensorimotor activation in the human thalamus at 9.4 Tesla

et al. 2023

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“…A gradient EPI sequence enables very rapid slice imaging by running all phase encodings after an excitation pulse of <90° (77° for 1.5 T and 80° for 3 T scanners). [ 10 ] This is achieved by rapid gradient switching to fill the k-space, leading to a set of tiny gradient echoes within the period of a single T2* decay [ 4 ]. fMRI with higher field strength (3.0 T and above) results in a higher signal-to-noise ratio (SNR), permitting greater BOLD disparity sensitivity with greater spatial resolution.…”

Section: Techniques For the Acquisition And Processing Of Bold Imagesmentioning

confidence: 99%

“…fMRI with higher field strength (3.0 T and above) results in a higher signal-to-noise ratio (SNR), permitting greater BOLD disparity sensitivity with greater spatial resolution. However, the susceptibility effects of deoxygenated hemoglobin are greater in high-strength fields and may cause more signal changes than anticipated [ 10 ]. In addition, compared to conventional MRI, fMRI is more prone to noise because of random variations of the BOLD signal [ 11 ].…”

Section: Techniques For the Acquisition And Processing Of Bold Imagesmentioning

confidence: 99%

Task-Based and Resting-State Functional MRI in Observing Eloquent Cerebral Areas Personalized for Epilepsy and Surgical Oncology Patients: A Review of the Current Evidence

Al-Arfaj

Al-Sharydah

Al-Suhibani

et al. 2023

JPM

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Functional magnetic resonance imaging (fMRI) is among the newest techniques of advanced neuroimaging that offer the opportunity for neuroradiologists, neurophysiologists, neuro-oncologists, and neurosurgeons to pre-operatively plan and manage different types of brain lesions. Furthermore, it plays a fundamental role in the personalized evaluation of patients with brain tumors or patients with an epileptic focus for preoperative planning. While the implementation of task-based fMRI has increased in recent years, the existing resources and evidence related to this technique are limited. We have, therefore, conducted a comprehensive review of the available resources to compile a detailed resource for physicians who specialize in managing patients with brain tumors and seizure disorders. This review contributes to the existing literature because it highlights the lack of studies on fMRI and its precise role and applicability in observing eloquent cerebral areas in surgical oncology and epilepsy patients, which we believe is underreported. Taking these considerations into account would help to better understand the role of this advanced neuroimaging technique and, ultimately, improve patient life expectancy and quality of life.

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fMRI of the Sensorimotor System

Cited by 2 publications

References 167 publications

Functional mapping of sensorimotor activation in the human thalamus at 9.4 Tesla

Functional mapping of sensorimotor activation in the human thalamus at 9.4 Tesla

Task-Based and Resting-State Functional MRI in Observing Eloquent Cerebral Areas Personalized for Epilepsy and Surgical Oncology Patients: A Review of the Current Evidence

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