Fluorosurfactants for medical nanoemulsions, their surface-active and biological properties

Stefanek, Agata; Łęczycka-Wilk, Katarzyna; Czarnocka-Śniadała, Sylwia; Frackowiak, Wojciech; Graffstein, Joanna; Ryżko, Agata; Nowak, Adriana; Ciach, Tomasz

doi:10.1016/j.colsurfb.2021.111603

Cited by 1 publication

(1 citation statement)

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“…Other nanotechnology-based carriers, particularly nanoemulsion (NEs) and microemulsions (MEs) have various applications in drug delivery research. 61 Furthermore, they are potential drug solubilizers that enhance penetration through their high surfactant/co-surfactant contents. 62 NEs are highly stable, with low toxicity and irritation, large drug loading capacity, and greatly improved drug bioavailability.…”

Section: Ocular Nano-drug Delivery Systemmentioning

confidence: 99%

Ten Years of Knowledge of Nano-Carrier Based Drug Delivery Systems in Ophthalmology: Current Evidence, Challenges, and Future Prospective

Zhang¹,

Jiao²,

Niu³

et al. 2021

IJN

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The complex drug delivery barrier in the eye reduces the bioavailability of many drugs, resulting in poor therapeutic effects. It is necessary to investigate new drugs through appropriate delivery routes and vehicles. Nanotechnology has utilized various nano-carriers to develop potential ocular drug delivery techniques that interact with the ocular mucosa, prolong the retention time of drugs in the eye, and increase permeability. Additionally, nano-carriers such as liposomes, nanoparticles, nano-suspensions, nano-micelles, and nano-emulsions have grown in popularity as an effective theranostic application to combat different microbial superbugs. In this review, we summarize the nano-carrier based drug delivery system developments over the last decade, particularly review the biology, methodology, approaches, and clinical applications of nano-carrier based drug delivery system in the field of ocular therapeutics. Furthermore, this review addresses upcoming challenges, and provides an outlook on potential future trends of nano-carrier-based drug delivery approaches in ophthalmology, and hopes to eventually provide successful applications for treating ocular diseases.

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Section: Ocular Nano-drug Delivery Systemmentioning

confidence: 99%