Fluoroquinolone resistance: mechanisms, impact on bacteria, and role in evolutionary success

Antimicrobial resistance in Enterococcus strains isolated from healthy domestic dogs

“…Instead, our result suggests that resistance to tigecycline is not so uncommon and could be a new threat in the therapy of infections. Diffuse resistance to fluoroquinolones was detected: this result seems to be related to their large employment in human and veterinary medicine due to their effectiveness against both Gram-positive and Gram-negative bacteria [21].…”

Prevalence and Antibiotic Resistance Pattern of Streptococcus Pneumoniae, Isolated From Invasive and Non-Invasive Infections in a Tertiary Care Hospital of Karachi.

“…The high occurrence of pneumococcal antibiotic resistance genes coupled with the ease of horizontal gene transfer have enhanced global dissemination of pneumococcal multi-drug resistance, which has significant impacts on clinical practice. Treatment guidelines for pneumococcal infections must be updated according to the changes in resistance patterns [30,31].…”

Quinolonas: Perspectivas actuales y mecanismos de resistencia

“…Incluso con las guías actuales, cuyo objetivo es preservar la eficacia de los antimicrobianos, la resistencia a quinolonas sigue ocurriendo en rangos que se incrementa en numerosas especies bacterianas y su uso varía alrededor del mundo. Grecia es el mayor usuario de quinolonas y tiene la mayor incidencia de aislados de Escherichia coli resistente a quinolonas, mientras que Suecia tiene la menor tasa de consumo y la menor incidencia de resistencia 31 . En Estados Unidos de América, un incremento de 40% en el uso de quinolonas ocasionó que se duplicara la tasa de resistencia hacia ciprofloxacina contra bacilos gramnegativos aislados en Unidades de Cuidados Intensivos.…”