Fluoroquinolone residues in raw cow's milk

Abstract

Navrátilová P., Borkovcová I., Vyhnálková J., Vorlová L. (2011): Fluoroquinolone residues in raw cow's milk. Czech J. Food Sci., 29: 641-646.The aim of the study was to monitore the levels of fluoroquinolone residues in bulk samples of raw cow's milk. The bulk samples of raw cow's milk (n = 150) were obtained from 58 different milk suppliers in the South Moravian and Vysočina Regions. The samples were analysed by reverse phase high-performance liquid chromatography method with fluorescence detection and gradient elution. 87.3% of the raw milk samples were positive for the fluoroquinolones residues. Flumequine was present in none of the samples. The levels of other fluoroquinolones investigated were below the recommended maximum residue limit. The results of the study indicate that fluoroquinolones are frequently administered to the dairy cows in spite of the recommendations of CVMP. The most frequently determined was enrofloxacin and its indicator residue, i.e. ciprofloxacin. An efficient control of the veterinary drugs residues in milk is very important to ensure the safety of the milk and milk products.

Rapid tests for detection of enrofloxacin residues in liquid milk

“…In the current study, it is pointed out that none of positive milk samples has enrofloxacin residues concentration exceeded the maximum residual limits (MRLs) set by different international standards like EU (European Commission 2010), China regulations (Rong-jie et al, 2014) and Japan Food Chemical Research Foundation (Change et al, 2010). Same results were set by Bilandžić et al (2011) and Navratilova et al (2011). While, higher results were reported by Moharana et al (2015).…”

“…Nearly similar percentages were reported by Bilandžić et al (2011) whom detected enrofloxacin residues in a percentage of 4.11 in raw milk samples. While the higher percentage were reported by Moharana et al (2015) and Navratilova et al (2011) Whom detected enrofloxacin residues with a percentage of 16.8 and 87.3; respectively in the examined raw milk samples.…”

“…The percentages of presence of quinolones residues in the examined milk samples were ranged between 14 and 20.6% (Table 1). Higher results were reported by Navratilova et al (2011) whom recorded that 87.3% of the raw milk samples were positive for the quinolones residues. While lower results were reported by Aguilera-Luiz et al (2008) and Nizamlıoğlu and Aydın (2012) whom recorded that none of the examined raw milk samples were found to be positive for quinolone residues.…”

“…1:97-103, MARCH, 2016 positive screening samples must be confirmed, generally with quantitative chromatographic methods (Sanz et al, 2015). Liquid chromatography (LC) is the most sensitive and specific analytical techniques used for the identification and quantitation of antibiotic residues in milk (Navratilova et al, 2011).…”

Effects of season and time of milking on spontaneous and induced lipolysis in bovine milk fat

“…Thus, the concentration of NEFA may reach a value detrimental to the health status of cows both prepartum (Poláková et al 2010) and postpartum (Herdt 2007). A wide range of dairy cows' production diseases are treated using antibiotics which affect the final quality of raw milk as well (Navrátilová et al 2011). Based on the facts mentioned above, we assume that differences in FFA contents can be detected among animals as well as among bulk tank samples collected in different seasons and milking times.…”