Fluoroquinolone (Levofloxacin) Induced Tendinopathy with Partial Tearing of the Achilles Tendon -A Case Report

Abstract

Adverse drug reactions (ADRs) are one of the key reasons for illness and death. For many years levofloxacin is known for its safety and unlike lines to cause ADR's. Tendinopathy is a rare complication that was documented and reported in adults as potentially serious and which can enhance the possibility of tendon rupture. Achilles Tendinopathy is a rare adverse effect of levofloxacin. This case report introduces a 78-yearold man diagnosed with partial tearing of Achilles tendon due to consumption of levofloxacin and drug methylprednisolone for treatment of chest infection and associated symptoms such as severe cough, breathlessness and wheezing sound. The assessment of ADR with Naranjo score was conducted and shows seven for this patient; accordingly, levofloxacin was the probable cause of this reaction. Early diagnosis of levofloxacin associated Achilles Tendinopathy and stopping the treatment may prevent tendon rupture. Food drug administration department also issued a cautionary warning specifying that fluoroquinolones, mainly levofloxacin can cause tendinopathy and tendon rupture in all ages patients. This possibility of risk of ADR's is furthermore increased in older patients generally over 60 years of age.