Fluorometric Determination of Phenol andp-Cresol in Urine by Precolumn High-Performance Liquid Chromatography Using 4-(N-Phthalimidinyl)benzenesulfonyl Chloride

Determination of Phenol and Chlorophenols at Single-Wall Carbon Nanotubes/Poly(3,4-ethylenedioxythiophene) Modified Glassy Carbon Electrode Using Flow Injection Amperometry

“…Various analytical methods, such as liquid chromatography (LC), gas chromatography (GC), capillary electrophoresis, and fluorometry, have been reported for the determination of phenols and phenol derivatives [3,5,[8][9][10]. These methods are sensitive, specific, and precise, but most of them are expensive and time consuming and require skilled technicians and some require derivatization procedures.…”

HPLC Determination of Acetaminophen in Saliva Based on Precolumn Fluorescence Derivatization with 12-(3,5-Dichloro-2,4,6-triazinyl)-benzo[d]benzo[1′,2′-6,5]isoindolo[1,2-b][1,3]thiazolidine

“…A large number of fluorescence derivatization reagents for the determination of phenolic hydroxyl groups in HPLC have been reported: e.g., 5-dimethylaminonaphthalene-1-sulfonyl chloride, 10 1-ethoxy-4-(dichloro-s-triazinyl)naphthalene, 11 4-dimethylaminonaphthalene-1-carbonitrile, 12 1-anthronitrile, 13 9-anthronitrile, 13 pyrene-1-carbonitrile, 14 1-pyrenesulfonyl chloride, 15 4-(N-phthalimidinyl)benzenesulfonyl chloride, 16 and 2-(4-carboxyphenyl)-5,6-dimethylbenzimidazole. 17 However, no data have been reported for the determination of APAP.…”

Analysis of phenols by high-performance liquid chromatography with pre-column derivatization by 2-(9-carbazole)-ethyl-chloroformate

“…In addition, because of double retention mechanism of phenols on C 18 column, the peak tailing is very serious with acetonitrile and water as mobile phase [18]. Therefore, suitable derivatization is also required [19][20][21][22]. Derivatization is time-consuming, but the derivatives can sometimes be determined at more selective wavelengths and may be easier to analyze by LC because of higher retention or better peak shapes.…”

“…Derivatization is time-consuming, but the derivatives can sometimes be determined at more selective wavelengths and may be easier to analyze by LC because of higher retention or better peak shapes. However, only a few labeling reagents have been used for this purpose, such as 2-methoxy-4-(2-phthalimidinyl)-phenylsulfonyl chloride [19], 4-(4,5-diphenyl-lH-imidazol-2-yl)benzoyl chloride [20,21], 4-(N-phthalimidinyl)benzenesulfonyl chloride [22], anthraquinone-2-sulfonyl chloride [23] and dansyl chloride [5-(dimethylamino)-1-naphthalenesulfonyl chloride] (Dns-Cl) [24].…”