Fluorodeoxyglucose Positron Emission Tomography/Magnetic Resonance Imaging

Bone biopsy protocol for advanced prostate cancer in the era of precision medicine

“…One patient was found to have 2 sclerotic lesions in the right iliac bone. We performed an additional sodium fluoride ( 18 F‐NaF) positron emission tomography (PET)‐magnetic resonance imaging (MRI) to identify the most metabolic active lesions . Based on the results, the biopsy plan subsequently was adjusted to target L5 vertebra and anterior superior iliac spine (Fig.…”

Current Status of Hybrid PET/MRI in Oncologic Imaging

“…Our initial experience with the use of 18 F-NaF PET/MRI in the diagnosis of bone metastases from prostate cancer is promising [45]. Although detection of bone metastases from prostate cancer is traditionally performed with bone scanning, that technique has a low specificity of 41% [46] because of overlap of bone metastases with benign conditions such as healing fractures, degenerative or inflammatory joint disease, Paget disease, benign neoplasms, or metabolic disorders [47, 48].…”

Disease-specific cardiovascular positron emission tomography/magnetic resonance imaging: a brief review of the current literature

“…Most cardiac sarcoidosis PET studies were done using the 18 F-FDG tracer, which detects inflammation, but at least one study investigated the tracer of 13 N-NH 3 , which detects tissue perfusion. Both tracers had similar sensitivity in detecting cardiac sarcoidosis (50), but 18 F-FDG may be more sensitive than 13 N-NH 3 in monitoring response to steroid therapy (50). When compared to MR, PET also has the added benefit of a comprehensive whole-body assessment to detect or monitor extracardiac sarcoidosis.…”

“…Multiple original studies and review articles investigated and speculated the utility of simultaneous cardiac PET/MR in myocardial infarct imaging (9)(10)(11)(12)(13)(14)(15) In a subsequent study, they shifted their attention to the areas around the acute myocardial infarction scar (the "at-risk" area) (10). Twenty-five patients who suffered from acute coronary occlusion and received interventional reperfusion underwent simultaneous cardiac 18 LGE are likely non-salvageable myocardium, whereas areas with no LGE but reduced 18 F-FDG uptake are likely "atrisk" salvageable myocardium.…”

“…Cardiac PET perfusion imaging is considered the reference technique for quantitative myocardial perfusion, due to its ability to quantify absolute myocardial blood flow (MBF) and coronary flow reserve, relative lack of attenuation artifact, and superior image quality (4). The most common PET perfusion tracers include 13 F-Flurpiridaz. MR perfusion stress test has been used more commonly in the last few years, and meta-analysis showed that it was at least non-inferior if not superior to SPECT or echo stress tests (5).…”