Fluoride release profile of a nanofilled resin-modified glass ionomer cement

Abstract

The present study aimed to compare the fluoride (F-) release pattern of a nanofilled resin-modified glass ionomer cement (GIC) (Ketac N100 - KN) with available GICs used in dental practice (resin-modified GIC - Vitremer - V; conventional GIC - Ketac Molar - KM) and a nanofilled resin composite (Filtek Supreme - RC). Discs of each material (n=6) were placed into 4 mL of deionized water in sealed polyethylene vials and shaken, for 15 days. F- release (μg F-/cm²) was measured each day using a fluoride-ion specific electrode. Cumulative F- release means were statistically analyzed by linear regression analysis. In order to analyze the differences among materials and the influence of time in the daily F- release, 2-way ANOVA test was performed (α=0.05). The linear fits between the cumulative F- release profiles of RC and KM and time were weak. KN and V presented a strong relationship between cumulative F- release and time. There were significant differences between the daily F- release overtime up to the third day only for GICs materials. The daily F- release means for RC were similar overtime. The results indicate that the F- release profile of the nanofilled resin-modified GIC is comparable to the resin-modified GIC.

Influence of Different Mechanisms of Fluoride Release from Adhesive Systems

“…The fluoride released from the material is capable of interfering in the enamel demineralization process and on the oral microbiota, even under conditions of high caries risk (7,9,10,18). That was also the main purpose of introducing the fluoride-containing adhesive systems on the market (2,7).…”

“…Among the intrinsic factors are permeability, material composition, specimen's geometry, surface treatment and finishing (9,12,18). Except for the adhesive composition, all the remaining factors were standardized in the present study.…”

“…The low amount of fluoride release from FLB could be related to extrinsic factors such as the storage medium, the experimental design and analytical methods used to evaluate the fluoride release behavior (5,9,19,20). The storage medium influences the fluoride release values, which vary if the storage solution is replaced daily or used cumulatively (19).…”

“…This behavior indicates that these materials may show a higher capacity of providing fluoride to the tooth structure at the moments when the Fluoride release from adhesive systems adjacent enamel is most susceptible to demineralization. Thus, when the cariogenic inhibition potential of a dental material is analyzed, the fluoride release pattern may be more important than the quantity of material (5,9). Clinically, components of saliva, acquired pellicle, pH, ion concentration and temperature may decrease the fluoride diffusion from the restorative materials.…”

“…Fluoride is important to the remineralization process of the tissue disorganized by caries, and it also interferes with dental plaque development and inhibits bacterial growth (6)(7)(8)(9)(10)(11). Therefore, fluoride-containing dental materials have been developed aiming at the reduction of secondary caries.…”