Fluorescent turn-off competitive immunoassay for biotin based on hydrothermally synthesized carbon dots

Yao, Wensong; Wu, Namei; Lin, Zhen; Chen, Jinyuan; Li, Shaoguang; Weng, Shaohuang; Zhang, Lingling; Liu, Ailin; Lin, Xinhua

doi:10.1007/s00604-017-2078-6

Cited by 17 publications

(6 citation statements)

References 23 publications

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“… 77 In addition, benefiting from the dual-model response to pH changing as well as the established analytical method, wound pH could be both predicted theoretically and estimated visually in the case of blood contamination and long-term observations. Besides applications in ions and pH sensing, CDs also show selectivity toward a wide range of biomolecules including amino acids (such as cysteine), 78 glutathione, 79 vitamins (such as vitamin B 12 , vitamin B 7 , ascorbic acid), 80 − 82 formaldehyde, 83 glucose, 84 DNA, and proteins, 61 , 85 − 87 which are associated with health issues and diseases. Therefore, CDs can provide valuable insights into the diagnostics and early precaution of diseases.…”

Section: Optical Applicationsmentioning

confidence: 99%

Carbon Dots: A New Type of Carbon-Based Nanomaterial with Wide Applications

2020

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Carbon dots (CDs), as a new type of carbon-based nanomaterial, have attracted broad research interest for years, because of their diverse physicochemical properties and favorable attributes like good biocompatibility, unique optical properties, low cost, ecofriendliness, abundant functional groups (e.g., amino, hydroxyl, carboxyl), high stability, and electron mobility. In this Outlook, we comprehensively summarize the classification of CDs based on the analysis of their formation mechanism, micro-/nanostructure and property features, and describe their synthetic methods and optical properties including strong absorption, photoluminescence, and phosphorescence. Furthermore, the recent significant advances in diverse applications, including optical (sensor, anticounterfeiting), energy (light-emitting diodes, catalysis, photovoltaics, supercapacitors), and promising biomedicine, are systematically highlighted. Finally, we envisage the key issues to be challenged, future research directions, and perspectives to show a full picture of CDs-based materials.

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Section: Optical Applicationsmentioning

confidence: 99%

Carbon Dots: A New Type of Carbon-Based Nanomaterial with Wide Applications

2020

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“…Carbon dots (CDs) are a kind of quasi-spherical particles with a diameter of less than 10 nm [1][2][3][4]. CDs possess u n i q u e o p t i c a l p r o p e r t i e s s u c h a s t u n a b l e photoluminescence (PL) and excitation dependent multicolor emission [5][6][7]. These properties result from the quantum confinement effect or conjugated π-domains [8][9][10].…”

Section: Introductionmentioning

confidence: 99%

The quenching of the fluorescence of carbon dots: A review on mechanisms and applications

et al. 2017

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Carbon dots (CDs) possess unique optical properties such as tunable photoluminescence (PL) and excitation dependent multicolor emission. The quenching and recovery of the fluorescence of CDs can be utilized for detecting analytes. The PL mechanisms of CDs have been discussed in previous articles, but the quenching mechanisms of CDs have not been summarized so far. Quenching mechanisms include static quenching, dynamic quenching, Förster resonance energy transfer (FRET), photoinduced electron transfer (PET), surface energy transfer (SET), Dexter energy transfer (DET) and inner filter effect (IFE). Following an introduction, the review (with 88 refs.) first summarizes the various kinds of quenching mechanisms of CDs (including static quenching, dynamic quenching, FRET, PET and IFE), the principles of these quenching mechanisms, and the methods of distinguishing these quenching mechanisms. This is followed by an overview on applications of the various quenching mechanisms in detection and imaging.

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“…83 CQDs are beneficial for sensing applications towards the detection of various bio-analytes including lysine, vitamin B2 (riboflavin), intracellular pH, Fe 3+ , hypochlorite (ClO − ), bilirubin (BR), vitamin B12 (cyanocobalamin), polysaccharide, ATP, cysteine (Cys), homocysteine (Hcy), glutathione (GSH) etc (Table 1). 62 a ,63–82,84–90,93 The sensing phenomenon by CQDs mostly relies on PET, FRET, IFE, static and dynamic quenching. In the case of static quenching, a non-fluorescent ground state complexation is observed via the interaction of CQDs with the quencher, which can be easily examined by UV-Vis absorption spectroscopy or lifetime values.…”

Section: Exploration Of Different Types Of Zero-dimensional Nanomater...mentioning

confidence: 99%

Recent progress in 0D optical nanoprobes for applications in the sensing of (bio)analytes with the prospect of global health monitoring and detailed mechanistic insights

et al. 2022

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Fluorescent turn-off competitive immunoassay for biotin based on hydrothermally synthesized carbon dots

Cited by 17 publications

References 23 publications

Carbon Dots: A New Type of Carbon-Based Nanomaterial with Wide Applications

Carbon Dots: A New Type of Carbon-Based Nanomaterial with Wide Applications

The quenching of the fluorescence of carbon dots: A review on mechanisms and applications

Recent progress in 0D optical nanoprobes for applications in the sensing of (bio)analytes with the prospect of global health monitoring and detailed mechanistic insights

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