Fluorescent Sensors for the Detection of Heavy Metal Ions in Aqueous Media

De, Nerea; Elosúa, César; Corres, Jesús M.; Arregui, Francisco J.

doi:10.3390/s19030599

Cited by 209 publications

(87 citation statements)

References 219 publications

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“…As a result, development of simple, rapid, and inexpensive methods for reliable on‐site detection of Cu 2+ is of great value. Fluorescent sensors in particular have attracted much interest due to their sensitivity, rapid response, and ease of use …”

Section: Introductionmentioning

confidence: 99%

Cu²⁺ sensing via noncovalent complexes of fluorescent whitening agents and imidazole‐based polymeric dye transfer inhibitors

Fernandes

Ugwu

2020

J of Applied Polymer Sci

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The fluorescence image taken by Fernandes and Ugwu shows conversion of a Cu 2+ insensitive fluorophore (bottom row) into a sensitive "turn-off" probe for the metal ion (top row) via complexation with a commercial imidazole polymer. This work introduces a synthesis and purification-free method for production of bright, 100% water-soluble fluorescent probes for Cu 2+ .Volume 137, Number 17 was mailed the week of February 3, 2020.ARTICLES 48596 High-toughness, environment-friendly solid epoxy resins: Preparation, mechanical performance, curing behavior, and thermal properties

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Section: Introductionmentioning

confidence: 99%

Cu²⁺ sensing via noncovalent complexes of fluorescent whitening agents and imidazole‐based polymeric dye transfer inhibitors

Fernandes

Ugwu

2020

J of Applied Polymer Sci

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“…However, both techniques result in trace level detection mechanisms. De-Acha et al [34] have summarized recent advances in phosphorescence sensors, and among the reported sensors, lead and copper ions have been detected in the range of 0 to 1 × 10 −5 M. Detection of the current method is within a similar range of 0 to 1 × 10 −6 M.…”

Section: Leaching Capacity Of the Intercalated Stilbenementioning

confidence: 96%

Trace Metal Detection in Aqueous Reservoirs Using Stilbene Intercalated Layered Rare-Earth Hydroxide Tablets

Omwoma

2020

Journal of Analytical Methods in Chemistry

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Contamination of aquatic reservoirs with metal ions is a slow gradual process that is not easy to detect. Consequences of the metal ions, especially the ones with high atomic numbers (heavy metals) at high concentrations, are severe and irreversible in aquatic reservoirs. As such, early detection mechanisms, especially at trace concentration, are essential for mitigation measures. In this work, a new, robust, and effective tool for trace metal detection and monitoring in aqueous solutions has been developed. Tablets (1 mm thick and similar to medicinal tablets) were manufactured from a powder comprising stilbene intercalated into gallery spaces of lanthanide-containing layered double hydroxides. The tablets were placed in a water column having different concentrations of Pb2+ and Cu2+ ions, and the water was allowed to flow for 45 minutes at a flow rate of 100 ml/s. Thereafter, the tablets were dried and made to powder, and their phosphorescence was measured. The gradual stilbene phosphorescence turnoff in the tablets from various concentrations of metal ions was correlated with sorption amounts. The tablets were able to detect effectively metal ions (up to Pb2+ 1.0 mmol/L and Cu2+ 5.0 mmol/L) in the aqueous media. As such, the concentrations of Pb2+ and Cu2+ ions at trace levels were determined in the test solutions. This method provides a real-time metal ion analysis and does not involve sampling of water samples for analysis in the laboratory.

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“…In addition to their widespread use as stand-alone affinity binding reagents in analytical chemistry, aptamers have been engineered into a variety of ligand-specific biosensors, termed aptasensors [9]. Aptasensors can be designed to integrate with a variety of readout methods, such as electrochemical aptasensors [10][11][12] fluorescent aptasensors [13,14], label-free aptasensors [15,16], and aptasensors designed to interface with nucleic acid signaling cascades [17,18] or specifically for detection of targets such as pathogens [19,20] or small molecules [7,21].…”

Section: Introductionmentioning

confidence: 99%

SELEX tool: a novel and convenient gel-based diffusion method for monitoring of aptamer-target binding

et al. 2020

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Background: Aptamers, single-stranded DNAs or RNAs, can be selected from a library containing random sequences using a method called Systematic Evolution of Ligands by EXponential Enrichment (SELEX). In SELEX, monitoring the enriching statuses of aptamer candidates during the process is a key step until today. Conformational change of an aptamer caused by target-binding in gel can be used to indicate its statuses of binding. Results: In this study, an easy-to-implement gel-based diffusion method (GBDM) was developed to monitor the interaction between enriched aptamer candidates and their targets. In order to prove the concept, characterization of aptamers targeting their targets including protein (thrombin) and non-protein molecules (acetamiprid, ATP, atrazine, profenofos and roxithromycin), respectively, were performed using mini gels. Our method has advantages over the common methods including easy performed with labor-and time-saving in experimental operation. The concept has been proven by monitoring enrichment of dynamic aptamer candidate libraries targeting a small molecule 2,2-bis(4-chlorophenyl) acetic acid (DDA) during SELEX process. A mini gel cassette was designed and fabricated by our laboratory to make mini agarose gels for diffusion with different directions. Conclusions:These results indicate that GBDM, in particular, chasing diffusion is suitable for monitoring the interaction between enriched aptamer candidates and their targets. These pioneering efforts are helpful for novel aptamer selection by breaking through the technical bottleneck of aptamer development and helpful for development of novel aptasensors.

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Fluorescent Sensors for the Detection of Heavy Metal Ions in Aqueous Media

Cited by 209 publications

References 219 publications

Cu²⁺ sensing via noncovalent complexes of fluorescent whitening agents and imidazole‐based polymeric dye transfer inhibitors

Cu²⁺ sensing via noncovalent complexes of fluorescent whitening agents and imidazole‐based polymeric dye transfer inhibitors

Trace Metal Detection in Aqueous Reservoirs Using Stilbene Intercalated Layered Rare-Earth Hydroxide Tablets

SELEX tool: a novel and convenient gel-based diffusion method for monitoring of aptamer-target binding

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Fluorescent Sensors for the Detection of Heavy Metal Ions in Aqueous Media

Cited by 209 publications

References 219 publications

Cu2+ sensing via noncovalent complexes of fluorescent whitening agents and imidazole‐based polymeric dye transfer inhibitors

Cu2+ sensing via noncovalent complexes of fluorescent whitening agents and imidazole‐based polymeric dye transfer inhibitors

Trace Metal Detection in Aqueous Reservoirs Using Stilbene Intercalated Layered Rare-Earth Hydroxide Tablets

SELEX tool: a novel and convenient gel-based diffusion method for monitoring of aptamer-target binding

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Product

Resources

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Cu²⁺ sensing via noncovalent complexes of fluorescent whitening agents and imidazole‐based polymeric dye transfer inhibitors

Cu²⁺ sensing via noncovalent complexes of fluorescent whitening agents and imidazole‐based polymeric dye transfer inhibitors