Fluorescent nitrogen and sulfur co-doped carbon dots from casein and their applications for sensitive detection of Hg 2+ and biothiols and cellular imaging

Xu, Shouming; Yang, Liu; Yang, Hong; Zhao, Kang; Li, Jianguo; Deng, Anping

doi:10.1016/j.aca.2017.01.037

Cited by 105 publications

(44 citation statements)

References 63 publications

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“…In recent years, with CQD preparation and surface functionalization modification technology continuously developing, suitable light intensity, emission wavelength, water solubility, biocompatibility, and performance have been improved. Consequently, the application of CQDs in the fields related to ion probes and biomolecular sensing, photocatalysis, luminescent materials, biological imaging, drug carriers, and disease treatment has made good progress.…”

Section: Introductionmentioning

confidence: 99%

Preparation and application of solvent‐modulated self‐doped N–S multicolour fluorescence carbon quantum dots

Zhao

2019

Luminescence

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In this paper, two types of carbon quantum dot (CQDs) were prepared using biocompatible L-methionine as the carbon source and urea as the nitrogen source and a onestep hydrothermal treatment. By changing the reaction solvents (deionized (DI) water and dimethylformamide (DMF)), the maximum emission of the resulting CQDs shifted from blue to red light. Specifically, the emission wavelength of the CQDs moved from 433 nm to 625 nm following embedding of a new functional group (-CONH-) on the surface of the CQDs. Photoluminescence quantum yields of the CQDs with blue and red emission reached 64% and 61%, respectively. The R-CQDs were used to detect metal ions and a linear relationship was demonstrated between ln(F/F 0 ) and Fe 3+ concentration in the range 0-0.5 mmol/L with a detection limit of 0.067 μM. Therefore these R-CQDs have great potential as fluorescent probes for Fe 3+ detection. We expect that the excellent water-soluble, biocompatible and optical properties of the CQDs developed in this work mean that they will be widely used to detect biological cells.KEYWORDS amino acids, carbon quantum dots, fluorescent properties, metal ion detection

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Section: Introductionmentioning

confidence: 99%

Preparation and application of solvent‐modulated self‐doped N–S multicolour fluorescence carbon quantum dots

Zhao

2019

Luminescence

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“…[15] The high-resolution O1s spectrum (Fig. 2c) can be deconvoluted into three peaks as C=O (531.4 eV), C-O-C (532.4 eV), and C-O (533.9 eV) with the corresponding atomic contents of 33.6%, 34.6%, and 31.8%, respectively [16] . It confirmed that oxygen-rich functional groups existed on the surface of CQDs.…”

Section: Resultsmentioning

confidence: 99%

Highly sensitive fluorescent probe for Cr3+ detection using carbon quantum dots

Huangfu¹,

Hao²,

Hao³

2018

Proceedings of the 2017 3rd International Forum on Energy, Environment Science and Materials (IFEESM 2017)

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Carbon quantum dots (CQDs) had been widely applied in the metal ions detection area due to their excellent optical properties and low toxicity. Herein, a series of CQDs with different sizes were prepared by a facile but effective hydrogen peroxide (H2O2) oxidative method using activated carbon as carbon source. Experimental results showed that the concentration of H2O2 aqueous solution had critical effect on the sizes and surface structure of CQDs. When H2O2 aqueous solution was 20 wt.%, the diameter of CQDs was 3.6 nm, and the fluorescent probe exhibited a good linear response to Cr 3+ in the concentration range from 0.2 to 55 μM with a detection limit of 0.2 μM. Through systematically analyzing FTIR, XPS and the optical properties of CQDs, the high sensitivity of CQDs for detecting Cr 3+ was attributed to the synergistic effect of the surface oxygen-containing functional groups and size of CQDs.

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“…Moreover, Xu et al optimized the molar ratios of the precursors-sodium citrate and diammonium phosphate (15:1, 19:1, 24:1, and 28:1), the reaction temperatures (140,150,160,170,200, and 220 • C), and reaction time periods (2, 4, 6, 8, and 10 h) in hydrothermal method to effectively synthesize N and P co-doped CQDs (with enhanced QY of 53.8%) for detection of Hg 2+ ions at an excitation wavelength of 440 nm [170]. Herein, the resultant calibration curve for Hg 2+ ions has exhibited a good linearity in a specific concentration range with LOD and time of 1 nM and 0.5 min, respectively.…”

Section: Mercury (Hg 2+ ) Ionsmentioning

confidence: 99%

“…Similarly, have also used a single precursor-glutathione (self-doping) to prepare N and S co-doped CQDs in hydrothermal process (6 h at 200 • C), where the resultant CQDs have exhibited blue emission and QY of 17.5%[149]. In another study, Xu et al (2017) used only casein (self-doping) as C, N, and S sources in pyrolysis strategy (4 h at 180 • C) to synthesize blue emitting N and S co-doped CQDs with QY of 31.8%[150] Ye et al (2017). synthesized different N and S co-doped CQDs (through self-doping) with blue emission via the pyrolysis carbonization (3 h at 300 • C) of diverse precursors-i.e., feathers, egg white, egg yolk, and manure from pigeon, resulting in QYs of 24.87%, 17.48%, 16.34%, and 33.50% correspondingly[151].…”

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confidence: 99%

Recent Advancements in Doped/Co-Doped Carbon Quantum Dots for Multi-Potential Applications

Kandasamy

2019

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Carbon quantum dots (CQDs)/carbon nanodots are a new class of fluorescent carbon nanomaterials having an approximate size in the range of 2–10 nm. The majority of the reported review articles have discussed about the development of the CQDs (via simple and cost-effective synthesis methods) for use in bio-imaging and chemical-/biological-sensing applications. However, there is a severe lack of consolidated studies on the recently developed CQDs (especially doped/co-doped) that are utilized in different areas of application. Hence, in this review, we have extensively discussed about the recent development in doped and co-doped CQDs (using elements/heteroatoms—e.g., boron (B), fluorine (F), nitrogen (N), sulphur (S), and phosphorous (P)), along with their synthesis method, reaction conditions, and/or quantum yield (QY), and their emerging multi-potential applications including electrical/electronics (such as light emitting diode (LED) and solar cells), fluorescent ink for anti-counterfeiting, optical sensors (for detection of metal ions, drugs, and pesticides/fungicides), gene delivery, and temperature probing.

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Fluorescent nitrogen and sulfur co-doped carbon dots from casein and their applications for sensitive detection of Hg 2+ and biothiols and cellular imaging

Cited by 105 publications

References 63 publications

Preparation and application of solvent‐modulated self‐doped N–S multicolour fluorescence carbon quantum dots

Preparation and application of solvent‐modulated self‐doped N–S multicolour fluorescence carbon quantum dots

Highly sensitive fluorescent probe for Cr3+ detection using carbon quantum dots

Recent Advancements in Doped/Co-Doped Carbon Quantum Dots for Multi-Potential Applications

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