Fluorescent nanoprobes for the sensing of gasotransmitters hydrogen sulfide (H2S), nitric oxide (NO) and carbon monoxide (CO)

Emerging analytical tools for the detection of the third gasotransmitter H2S, a comprehensive review

“…glutathione, cysteine …) or other ions present in the blood or tissues under investigation. Hence, a plethora of different analytical methods has evolved for H 2 S measurements such as fluorescence-based assays [18] , colorimetric sensors [19] , chromatographic methods (HPLC and GC) [20] and electrochemical methods (ion-selective electrodes and polarographic H 2 S sensors) [21] . However, each of these techniques has its advantages and limitations.…”

“…Several reviews have reported on the different analytical approaches applied for the determination of this gaseous signaling molecule [18] , [22] , [23] , [24] , [25] , [26] , [27] , [28] . However, most of these reviews focused only on spectroscopic techniques with special emphasis on probe materials [18] , [19] , [29] , design strategies [27] , [30] , and detection mechanisms [28] , [31] . Asides, very few reports have discussed other analytical methodologies such as electrochemical and chromatographic methods [21] , [22] .…”

Fluorescent probes based on nucleophilic aromatic substitution reactions for reactive sulfur and selenium species: Recent progress, applications, and design strategies

“…Because RSS and RSeS are prone to deprotonation, and their amounts in vivo are very small, the development of RSS- and RSeS-specific fluorescent probes for intracellular or in vivo targeting is very challenging [7] , [8] . Observing the endogenous or exogenous RSS and RSeS in cells or animals is an important application of fluorescent probes [67] , [70] , [71] , [72] . RSS- and RSeS-specific fluorescent probes should be able to provide insight into changes in specific RSS and RSeS in healthy and diseased cells and biological systems [73] , [74] , [75] .…”

State-of-the-Art Technology of Model Organisms for Current Human Medicine

“…This can be achieved through the high-throughput screening (HTS), phenotype screening, and virtual screening of precision medicine, such as in human immunodeficiency infection using bacteria [7], seizures in zebrafish [8], and Duchenne muscular dystrophy in animals such as worms, fruit flies, and zebrafish [9]. This is also important in the fields of detection and diagnosis, such as the use of organic and metal complex-based fluorescent sensing nanoprobes to monitor the level of nitric oxide, an important gaseous signaling molecule related to various human diseases, by using animals, such as mice and zebrafish, in vitro and in vivo (Figures 1 and 2) [10][11][12].…”