Fluorescent immunosensor based on fluorescence resonance energy transfer between CdSe/ZnS quantum dots and Au nanorods for PRRSV detection

Fluorescent detection of emerging virus based on nanoparticles: From synthesis to application

“…Combination with quantum dots enables virus detection and quantification. Based on immunomagnetic separation, a new FRET assay for the detection of Porcine reproductive and respiratory syndrome virus (PRRSV) was constructed using CdSe/ZnS as fluorescence donors and AuNPs as fluorescence receptors, which enable the detection of low concentrations of PRRSV in pig serum in a wide range (10 1 -3.5 × 10 4 TCID 50 /mL) [ 162 ]. However, in complicated samples, single QDs exhibit inadequate luminescence intensity and poor photostability.…”

Bio-Tailored Sensing at the Nanoscale: Biochemical Aspects and Applications

“…The quenching effect induced via 0D and 2D nanomaterials is a very common tool exploited in immune-based sensing and is reported by other studies, as for instance antibodies-conjugated CdSe-ZnSQDs and AuNRs to detect porcine reproductive and respiratory syndrome virus in swine serum [ 114 ] and rhodamine-labelled affinity peptides adsorbed onto WS 2 -Pt-Fe 2 O 3 polycaprolactone micromotors for detection of bacterial lipopolysaccharides [ 115 ].…”

A WOx/MoOx hybrid oxide based SERS FET and investigation on its tunable SERS performance

“…The CM effect of semiconducting materials like TiO 2 , ZnO, MoS 2 , WSe 2 and MoO 3 has been extensively reported. [13][14][15][16][17][18] Practically, the SERS performance contributed by the CM is enhanced by regulating the defect density or levels to match the orbital energy levels of the adsorbed molecules, and boost the charge transfer efficiency. [19][20][21] For example, Cong et al reported impressive SERS performance measured on W 18 O 49 nanowires prepared by the hydrothermal method.…”