Fluorescent anionic cyanine plasma membrane probes for live cell andin vivoimaging
Dmytro I. Danylchuk,
Igor Khalin,
Yelisetty V. Suseela
et al.
Abstract:Proper staining of cell plasma membrane is indispensable for fluorescence imaging. Herein, we present an array of five anionic cyanine-based turn-on plasma membrane probes with emission spanning from green to near infrared. They are analogous of commonly used MemBright probes family, where two zwitterionic anchor groups are replaced with anionic sulfonates with dodecyl chains. The developed probes provide selective wash-free staining of plasma membranes of live cells in vitro, featuring improved brightness and… Show more
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