Fluorescence turn-on detection of fenitrothion using gold nanoparticle quenched fluorescein and its separation using superparamagnetic iron oxide nanoparticle

Nebu, John; Devi, J.S. Anjali; Aparna, R.S.; Aswathy, B.; Lekha, G.M.; George, Sony

doi:10.1016/j.snb.2018.08.153

Cited by 35 publications

(17 citation statements)

References 44 publications

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“…Magnetic iron oxide nanoparticles (NPs), such as magnetite (Fe 3 O 4 ) and maghemite (γ-Fe 2 O 3 ), have been found and applied in a wide range of biomedical applications [1,2,3,4,5,6,7,8,9], including magnetic resonance imaging, magnetic hyperthermia, cancer therapy, and drug delivery; they also find applications in catalysis [10,11,12] and in magnetic separation [13,14]. Among other metal nanoparticles, iron oxide nanoparticles have been more extensively studied in clinical practice [15].…”

Section: Introductionmentioning

confidence: 99%

Fe3O4 Nanoparticles for Complex Targeted Delivery and Boron Neutron Capture Therapy

et al. 2019

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Magnetic Fe3O4 nanoparticles (NPs) and their surface modification with therapeutic substances are of great interest, especially drug delivery for cancer therapy, including boron-neutron capture therapy (BNCT). In this paper, we present the results of boron-rich compound (carborane borate) attachment to previously aminated by (3-aminopropyl)-trimethoxysilane (APTMS) iron oxide NPs. Fourier transform infrared spectroscopy with Attenuated total reflectance accessory (ATR-FTIR) and energy-dispersive X-ray analysis confirmed the change of the element content of NPs after modification and formation of new bonds between Fe3O4 NPs and the attached molecules. Transmission (TEM) and scanning electron microscopy (SEM) showed Fe3O4 NPs’ average size of 18.9 nm. Phase parameters were studied by powder X-ray diffraction (XRD), and the magnetic behavior of Fe3O4 NPs was elucidated by Mössbauer spectroscopy. The colloidal and chemical stability of NPs was studied using simulated body fluid (phosphate buffer—PBS). Modified NPs have shown excellent stability in PBS (pH = 7.4), characterized by XRD, Mössbauer spectroscopy, and dynamic light scattering (DLS). Biocompatibility was evaluated in-vitro using cultured mouse embryonic fibroblasts (MEFs). The results show us an increasing of IC50 from 0.110 mg/mL for Fe3O4 NPs to 0.405 mg/mL for Fe3O4-Carborane NPs. The obtained data confirm the biocompatibility and stability of synthesized NPs and the potential to use them in BNCT.

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Section: Introductionmentioning

confidence: 99%

Fe3O4 Nanoparticles for Complex Targeted Delivery and Boron Neutron Capture Therapy

et al. 2019

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“…This phenomenon involving metal nanoparticles functionalized to a fluorophore can be exploited to detect environmental pollutions [ 60 , 61 , 62 , 63 , 64 , 65 ]. It is possible to identify two sensor classes.…”

Section: Physical Aspects Behind Fluorescence Response To Environmmentioning

confidence: 99%

“…Many transducer components operate by modulating the quenching role of metal NPs with respect to fluorophores active in the spectral region of the Au [ 61 , 63 , 110 , 111 ] or Au-Ag plasmon resonance [ 112 ]. A fluorescent sensor for the detection of thiodicarb has been constructed using Rhodamine B (RB) functionalized AuNPs.…”

Section: Recent Developments On Pesticides Detectionmentioning

confidence: 99%

Metal Nanostructures for Environmental Pollutant Detection Based on Fluorescence

Burratti

Ciotta

et al. 2021

Nanomaterials

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Heavy metal ions and pesticides are extremely dangerous for human health and environment and an accurate detection is an essential step to monitor their levels in water. The standard and most used methods for detecting these pollutants are sophisticated and expensive analytical techniques. However, recent technological advancements have allowed the development of alternative techniques based on optical properties of noble metal nanomaterials, which provide many advantages such as ultrasensitive detection, fast turnover, simple protocols, in situ sampling, on-site capability and reduced cost. This paper provides a review of the most common photo-physical effects impact on the fluorescence of metal nanomaterials and how these processes can be exploited for the detection of pollutant species. The final aim is to provide readers with an updated guide on fluorescent metallic nano-systems used as optical sensors of heavy metal ions and pesticides in water.

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“…Superparamagnetic iron oxide nanoparticles (SPION) have inherent beneficial characteristics, including magnetic properties, magnetized under external magnetic field, biocompatibility, high dispersivity after coating with biocompatible substance, cellular uptake, and a short blood half-life. These benefits are the most effective parameters for transporting drugs, proteins, and probes for nanomedicinal applications [13,14].…”

Section: Introductionmentioning

confidence: 99%

Magnetofluorescent Nanocomposite Comprised of Carboxymethyl Dextran Coated Superparamagnetic Iron Oxide Nanoparticles and β-Diketon Coordinated Europium Complexes

Han

Lee

et al. 2019

Nanomaterials

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Red emitting europium (III) complexes Eu(TFAAN)3(P(Oct)3)3 (TFAAN = 2-(4,4,4-Trifluoroacetoacetyl)naphthalene, P(Oct)3 = trioctylphosphine) chelated on carboxymethyl dextran coated superparamagnetic iron oxide nanoparticles (CMD-SPIONs) was synthesized and the step wise synthetic process was reported. All the excitation spectra of distinctive photoluminesces were originated from f-f transition of EuIII with a strong red emission. The emission peaks are due to the hypersensitive transition 5D0→7F2 at 621 nm and 5D0→7F1 at 597 nm, 5D0→7F0 at 584 nm. No significant change in PL properties due to addition of CMD-SPIONs was observed. The cytotoxic effects of different concentrations and incubation times of Eu(TFAAN)3(P(Oct)3)3 chelated CMD-SPIONs were evaluated in HEK293T and HepG2 cells using the WST assay. The results imply that Eu(TFAAN)3(P(Oct)3)3 chelated CMD-SPIONs are not affecting the cell viability without altering the apoptosis and necrosis in the range of 10 to 240 μg/mL concentrations.

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Fluorescence turn-on detection of fenitrothion using gold nanoparticle quenched fluorescein and its separation using superparamagnetic iron oxide nanoparticle

Cited by 35 publications

References 44 publications

Fe3O4 Nanoparticles for Complex Targeted Delivery and Boron Neutron Capture Therapy

Fe3O4 Nanoparticles for Complex Targeted Delivery and Boron Neutron Capture Therapy

Metal Nanostructures for Environmental Pollutant Detection Based on Fluorescence

Magnetofluorescent Nanocomposite Comprised of Carboxymethyl Dextran Coated Superparamagnetic Iron Oxide Nanoparticles and β-Diketon Coordinated Europium Complexes

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