Fluorescence sensor for volatile trace explosives based on a hollow core photonic crystal fiber

Yang, Ji; Shen, Rui; Yan, Peixin; Liu, Yunhong; Li, Xueming; Zhang, Peng; Chen, Weimin

doi:10.1016/j.snb.2019.127585

Cited by 27 publications

(9 citation statements)

References 24 publications

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“…Ensuring that only the desired channels are exposed to the functionalizing process requires a method of capping and selectively unsealing the cross-section and makes use of the fact that the central analyte channel is of a larger diameter than those in the outer ring of photonic cladding. A creative method using UV-curable adhesive has been demonstrated by Yang (2020) ( Figure 3 e) [ 145 ]. Beyond those considerations, various chemistries suitable for functionalizing glass or polymers (typical PCF materials) are employed [ 146 ].…”

Section: Photonic Crystal Fibers (Pcfs) For Fluorescence-based Applic...mentioning

confidence: 99%

“…( d ) A schematic for the thermal pulling of a preform into a thin fiber with the same structure, adapted with permission from [ 142 ]. ( e ) A schematic of the multiple cleavage method for selective filling of the hollow core with a fluorescent species, adapted with permission from [ 145 ].…”

Section: Photonic Crystal Fibers (Pcfs) For Fluorescence-based Applic...mentioning

confidence: 99%

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Photonic Crystal Enhanced Fluorescence: A Review on Design Strategies and Applications

et al. 2023

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Nanoscale fluorescence emitters are efficient for measuring biomolecular interactions, but their utility for applications requiring single-unit observations is constrained by the need for large numerical aperture objectives, fluorescence intermittency, and poor photon collection efficiency resulting from omnidirectional emission. Photonic crystal (PC) structures hold promise to address the aforementioned challenges in fluorescence enhancement. In this review, we provide a broad overview of PCs by explaining their structures, design strategies, fabrication techniques, and sensing principles. Furthermore, we discuss recent applications of PC-enhanced fluorescence-based biosensors incorporated with emerging technologies, including nucleic acids sensing, protein detection, and steroid monitoring. Finally, we discuss current challenges associated with PC-enhanced fluorescence and provide an outlook for fluorescence enhancement with photonic-plasmonics coupling and their promise for point-of-care biosensing as well monitoring analytes of biological and environmental relevance. The review presents the transdisciplinary applications of PCs in the broad arena of fluorescence spectroscopy with broad applications in photo-plasmonics, life science research, materials chemistry, cancer diagnostics, and internet of things.

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Section: Photonic Crystal Fibers (Pcfs) For Fluorescence-based Applic...mentioning

confidence: 99%

Section: Photonic Crystal Fibers (Pcfs) For Fluorescence-based Applic...mentioning

confidence: 99%

Photonic Crystal Enhanced Fluorescence: A Review on Design Strategies and Applications

et al. 2023

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“…In recent years, PCF has emerged as a promising material for fabrication of sensors for the assay of different targets. For example, Chen et al proposed a novel hollow-core PCF volatile trace explosive sensor based on the fluorescence quenching [ 42 ]; Wang et al developed a hollow-core-PCF-based miniaturized sensor for the detection of aggregation-induced-emission molecules [ 43 ]; Yang et al developed a sensitive PCF-based immunosensor for the detection of alpha fetoprotein [ 44 ].…”

Section: Introductionmentioning

confidence: 99%

A photonic crystal fiber–based fluorescence sensor for simultaneous and sensitive detection of lactic acid enantiomers

Chi

et al. 2022

Anal Bioanal Chem

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Graphical abstract A photonic crystal fiber (PCF)–based fluorescence sensor is developed for rapid and sensitive detection of lactic acid (LA) enantiomers in serum samples. The sensor is fabricated by chemical binding dual enzymes on the inner surface of the PCF with numerous pore structures and a large specific surface area, which is suitable to be utilized as an enzymatic reaction carrier. To achieve simultaneous detection of l -LA and d -LA, the PCF with an aldehyde-activated surface is cut into two separate pieces, one of which is coated with l -LDH/GPT enzymes and the other with d -LDH/GPT enzymes. By being connected and carefully aligned to each other by a suitable sleeve tube connector, the responses of both l -LA and d -LA sensors are determined by laser-induced flourescence (LIF) detection. With the aid of enzyme-linked catalytic reactions, the proposed PCF sensor can greatly improve the sensitivity and analysis speed for the detection of LA enantiomers. The PCF sensor exhibits a low limit of detection of 9.5 μM and 0.8 μM, and a wide linear range of 25–2000 μM and 2–400 μM for l -LA and d -LA, respectively. The sensor has been successfully applied to accurate determination of LA enantiomers in human serum with satisfactory reproducibility and stability. It is indicated that the present PCF sensors would be used as an attractive analytical platform for quantitative detection of trace-amount LA enantiomers in real biological samples, and thus would play a role in disease diagnosis and clinical monitoring in point-of-care testing. Supplementary Information The online version contains supplementary material available at 10.1007/s00216-021-03788-5.

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“…As the vibrational transitions of gaseous specimens are usually located in the nearor mid-IR band, the advantages of optical gas sensors are highly selective based on the molecular signature spectra. Particularly for fiber-waveguide schemes, the gas, which fills in the hollow core of a fiber waveguide and meets the guided wave, can be identified by analyzing the variations of transmittance or reflectance of the guided wave [8,9]. A low concentration of gas, equal to or less than several parts in 10 6 (parts per million, ppm), can thus be identified.…”

Section: Introductionmentioning

confidence: 99%

Volatile Gas Sensing through Terahertz Pipe Waveguide

You

Wang

et al. 2020

Sensors

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Gas sensing to recognize volatile liquids is successfully conducted through pipe-guided terahertz (THz) radiation in a reflective and label-free manner. The hollow core of a pipe waveguide can efficiently deliver the sensing probe of the THz confined waveguide fields to any place where dangerous vapors exist. Target vapors that naturally diffuse from a sample site into the pipe core can be detected based on strong interaction between the probe and analyte. The power variation of the THz reflectance spectrum in response to various types and densities of vapors are characterized experimentally using a glass pipe. The most sensitive THz frequency of the pipe waveguide can recognize vapors with a resolution at a low part-per-million level. The investigation found that the sensitivity of the pipe-waveguide sensing scheme is dependent on the vapor absorption strength, which is strongly related to the molecular amount and properties including the dipole moment and mass of a gas molecule.

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Fluorescence sensor for volatile trace explosives based on a hollow core photonic crystal fiber

Cited by 27 publications

References 24 publications

Photonic Crystal Enhanced Fluorescence: A Review on Design Strategies and Applications

Photonic Crystal Enhanced Fluorescence: A Review on Design Strategies and Applications

A photonic crystal fiber–based fluorescence sensor for simultaneous and sensitive detection of lactic acid enantiomers

Volatile Gas Sensing through Terahertz Pipe Waveguide

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