Fluorescence–remission sensoring of skin tumours: preliminary results

Wollina, Uwe; Nelskamp, Cornelia; Scheibe, Armin; Faßler, D.; Schmidt, W.

doi:10.1111/j.1600-0846.2007.00252.x

Cited by 7 publications

(10 citation statements)

References 23 publications

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“…We developed an optimized measuring device (FRIS -FluorescenceRemission-Imaging-Sensor) combining sensors for fluorescence, remission and digital imaging with a white light LED-ring illumination, a drilled mirror and fibre optics 13 (Fig. 1).…”

Section: Frismentioning

confidence: 99%

Fluorescence remission spectroscopy of psoriatic lesions and the effect of topical anthralin therapy

Wollina

Koch

et al. 2009

Acad Dermatol Venereol

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Section: Frismentioning

confidence: 99%

Fluorescence remission spectroscopy of psoriatic lesions and the effect of topical anthralin therapy

Wollina

Koch

et al. 2009

Acad Dermatol Venereol

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“…OCT, HFUS, and MRI can acquire full thickness, vertical optical sections, however their resolution is relatively limited and can not reach the cellular level. There are also some recently developed techniques for skin cancer imaging, such as fl uorescence remission sensoring (Wollina et al 2007), Raman spectroscopy (Lieber et al 2008;Naito et al 2008), and photoacoustic microscopy (Zhang et al 2006).…”

Section: Anatomical Imagingmentioning

confidence: 99%

“…Besides the abovementioned modalities, several other imaging methods still at the early stages of development are also suitable for skin-related imaging. These techniques include fluorescence remission sensoring (Wollina et al 2007), Raman spectroscopy (Lieber et al 2008;Naito et al 2008), and photoacoustic microscopy (Zhang et al 2006). Fluorescence remission sensoring was applied in a preliminary study to differentiate the subtypes of NMSC (Wollina et al 2007).…”

Section: Other Anatomical Imaging Techniquesmentioning

confidence: 99%

“…These techniques include fluorescence remission sensoring (Wollina et al 2007), Raman spectroscopy (Lieber et al 2008;Naito et al 2008), and photoacoustic microscopy (Zhang et al 2006). Fluorescence remission sensoring was applied in a preliminary study to differentiate the subtypes of NMSC (Wollina et al 2007). Some differences were observed between BCC and actinic keratoses, which may aid in the accurate diagnosis of skin cancer (Wollina et al 2007).…”

Section: Other Anatomical Imaging Techniquesmentioning

confidence: 99%

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Anatomical and molecular imaging of skin cancer

Hong

Sun²,

Cai

2008

CCID

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Skin cancer is the most common form of cancer types. It is generally divided into two categories: melanoma (∼ 5%) and nonmelanoma (∼ 95%), which can be further categorized into basal cell carcinoma, squamous cell carcinoma, and some rare skin cancer types. Biopsy is still the gold standard for skin cancer evaluation in the clinic. Various anatomical imaging techniques have been used to evaluate different types of skin cancer lesions, including laser scanning confocal microscopy, optical coherence tomography, high-frequency ultrasound, terahertz pulsed imaging, magnetic resonance imaging, and some other recently developed techniques such as photoacoustic microscopy. However, anatomical imaging alone may not be suffi cient in guiding skin cancer diagnosis and therapy. Over the last decade, various molecular imaging techniques (in particular single photon emission computed tomography and positron emission tomography) have been investigated for skin cancer imaging. The pathways or molecular targets that have been studied include glucose metabolism, integrin α v β 3 , melanocortin-1 receptor, high molecular weight melanoma-associated antigen, and several other molecular markers. Preclinical molecular imaging is thriving all over the world, while clinical molecular imaging has not lived up to the expectations because of slow bench-to-bedside translation. It is likely that this situation will change in the near future and molecular imaging will truly play an important role in personalized medicine of melanoma patients.

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“…However, objective evaluation using standard techniques, such as dermatoscopy does not provide sufficient discrimination between benign and malignant forms [1]. Therefore optical techniques are applied for achievement of better diagnosis for skin neoplasia.…”

Section: Introductionmentioning

confidence: 99%

Development of Low-Cost Photodynamic Therapy Device

et al. 2007

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Photodiagnosis and photodynamic therapy of non-melanoma skin cancers using delta-aminolevulinic acid/protoporphyrin IX (5-ALA/PpIX) give a combined application with broadest dissemination in the current clinical practice. The problems with using of lasers as light sources are the expenses associated with the operation of these types of installations. This is why we test the capability of cheaper sources -light-emitting diodes at 405 nm for fluorescence excitation of PpIX and 635 nm for photodynamic action initiation. A LED matrix is developed in our laboratory using two types of LEDs and a combined photodiagnosis/photodynamic theory device applicable for clinical practice is built. Geometrically matrix is formed in such way that power density at 635 nm is about 40 mW/cm 2 , which allow to reach treatment doses for a 15-20 min irradiation depending of the lesion size in the focus of the system. The therapeutic mode of system developed can be used also with some other photosensitizers from the porphyrins derivatives family.

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Fluorescence–remission sensoring of skin tumours: preliminary results

Abstract: A combination of fluorescence and remission readings of skin provides objective data in NMSC. We developed the FRIS equipment that allows a reproducible measurement and easy handling.

Cited by 7 publications

References 23 publications

Fluorescence remission spectroscopy of psoriatic lesions and the effect of topical anthralin therapy

Fluorescence remission spectroscopy of psoriatic lesions and the effect of topical anthralin therapy

Anatomical and molecular imaging of skin cancer

Development of Low-Cost Photodynamic Therapy Device

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