Fluorescence lateral flow immunoassay based point-of-care nanodiagnostics for orthopedic implant-associated infection

Borse, Vivek; Srivastava, Rohit

doi:10.1016/j.snb.2018.10.034

Cited by 64 publications

(35 citation statements)

References 39 publications

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“…Wang et al described a ZnO biosensor for CRP which had a detection limit of 100 ng/mL using a quartz crystal microbalance [18] and Ibupoto et al described the use of ZnO nanorods to measure CRP using a potentiometric technique which was able to detect 10 ng/mL CRP [19]. Borse and Srivastava described a lateral flow technology using quantum dots as the detection technology which gave a detection limit of 300 ng/mL for CRP [20].…”

Section: Resultsmentioning

confidence: 99%

A Copper Oxide/Zinc Oxide Composite Nano-Surface for Use in a Biosensor

et al. 2019

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In this study, biosensors based on zinc oxide–copper oxide composite nano-surfaces were prepared using a simple and inexpensive distributed colloidal technique. Combinations of mixed dispersions with volume ratios of 1:1, 1:2 and 2:1 ZnO:CuO were compared. The uniform nano-crystalline sensor surfaces on polyethylene terephthalate (PET) were analysed using scanning electron microscopy (SEM), Atomic Force Microscopy (AFM) and Raman Spectroscopy. The ZnO–CuO composite biosensor nano-surfaces showed a significantly increased impedimetric signal compared with pure ZnO nanocrystals, and the maximum output was achieved with a volume ratio of 1:2 ZnO/CuO. The antibody capture of C-reactive protein (CRP) on the nano-surfaces was used to demonstrate the enhanced signal generated with increasing amounts of CuO in the nano-surface.

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Section: Resultsmentioning

confidence: 99%

A Copper Oxide/Zinc Oxide Composite Nano-Surface for Use in a Biosensor

et al. 2019

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“…The development of simple, rapid, easy-to-use, and inexpensive POC tests will beneficial toward providing clinical care in developed countries as well as in the resource-limited developing world [ 10 , 11 ]. Recent developments in lateral flow immunoassay (LFIA) techniques address all the criteria necessary for their application as POC diagnostic tests [ 99 ]. LFIA facilitates the identification of pathogens in a broad range of biological samples (e.g., whole blood, plasma, serum, saliva, and other sources) together with evaluation and confirmation of results by visual inspection [ 100 ].…”

Section: Methods For Identifying Infectious Agentsmentioning

confidence: 99%

Emerging Options for the Diagnosis of Bacterial Infections and the Characterization of Antimicrobial Resistance

Rentschler

Kaiser

Deigner

2021

IJMS

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Precise and rapid identification and characterization of pathogens and antimicrobial resistance patterns are critical for the adequate treatment of infections, which represent an increasing problem in intensive care medicine. The current situation remains far from satisfactory in terms of turnaround times and overall efficacy. Application of an ineffective antimicrobial agent or the unnecessary use of broad-spectrum antibiotics worsens the patient prognosis and further accelerates the generation of resistant mutants. Here, we provide an overview that includes an evaluation and comparison of existing tools used to diagnose bacterial infections, together with a consideration of the underlying molecular principles and technologies. Special emphasis is placed on emerging developments that may lead to significant improvements in point of care detection and diagnosis of multi-resistant pathogens, and new directions that may be used to guide antibiotic therapy.

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“…Nanobiosensors-based lateral flow immunosensing have revolutionized the field of diagnostics [ [86] , [87] , [88] , [89] , [90] , [91] ] and present tremendous potential for enhancement in oral cancer diagnostics. The field of biosensing has emerged in the recent past for the development of techniques and devices that can precisely target cancer cells or its biomarkers.…”

Section: Techniques Used For Diagnosis Of Oral Cancermentioning

confidence: 99%

Oral cancer diagnosis and perspectives in India

Borse

Konwar

Buragohain

2020

Sensors International

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222

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Globally, oral cancer is the sixth most common type of cancer with India contributing to almost one-third of the total burden and the second country having the highest number of oral cancer cases. Oral squamous cell carcinoma (OSCC) dominates all the oral cancer cases with potentially malignant disorders, which is also recognized as a detectable pre-clinical phase of oral cancer. Tobacco consumption including smokeless tobacco, betel-quid chewing, excessive alcohol consumption, unhygienic oral condition, and sustained viral infections that include the human papillomavirus are some of the risk aspects for the incidence of oral cancer. Lack of knowledge, variations in exposure to the environment, and behavioral risk factors indicate a wide variation in the global incidence and increases the mortality rate. This review describes various risk factors related to the occurrence of oral cancer, the statistics of the distribution of oral cancer in India by various virtues, and the socio-economic positions. The various conventional diagnostic techniques used routinely for detection of the oral cancer are discussed along with advanced techniques. This review also focusses on the novel techniques developed by Indian researchers that have huge potential for application in oral cancer diagnosis.

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Fluorescence lateral flow immunoassay based point-of-care nanodiagnostics for orthopedic implant-associated infection

Cited by 64 publications

References 39 publications

A Copper Oxide/Zinc Oxide Composite Nano-Surface for Use in a Biosensor

A Copper Oxide/Zinc Oxide Composite Nano-Surface for Use in a Biosensor

Emerging Options for the Diagnosis of Bacterial Infections and the Characterization of Antimicrobial Resistance

Oral cancer diagnosis and perspectives in India

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