Fluorescence Imaging for Surgeons

Dip, Fernando; Ishizawa, Takeaki; Kokudo, Norihiro; Rosenthal, Raúl J.

doi:10.1007/978-3-319-15678-1

Cited by 17 publications

(2 citation statements)

References 10 publications

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“…Studies have suggested that coupling of a CEA antibody with ICG could enable the detection of such lesions with this technology. 23,24 Furthermore, not all superficial lesions demonstrated ICG uptake. We do not have a direct explanation of this failure, but assume relation to patient and tumor specific factors, which could be investigated in future studies.…”

Section: Discussionmentioning

confidence: 97%

A comparison of indocyanine green fluorescence and laparoscopic ultrasound for detection of liver tumors

Köse

Kahramangil

Aydın

et al. 2020

HPB

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Background: Indocyanine green (ICG) fluorescence imaging (ICG-FI) has been suggested for intraoperative identification of liver tumors. We aim to compare the intraoperative diagnostic utility of this imaging modality with laparoscopic ultrasound (LUS).Methods: This is an IRB-approved prospective study. ICG was administered intravenously 1-2 days before surgery. The findings on ICG-FI were compared to those on preoperative cross-sectional imaging (POCSI), LUS, diagnostic laparoscopy (DL). Results: A total of 144 lesions (62 superficial [visible on DL] and 82 deep) were detected in the study patients. POCSI identified 74%, LUS identified 92%, and ICG-FI identified 43%. ICG-FI detection rate was higher for superficial (95%) versus deep lesions (4%). 3% (4/144) of all lesions were seen only on ICG-FI. However, all of these lesions were small and superficial lesions that were apparent on DL. Conclusion:Although ICG-FI allowed detection of small superficial lesions that were not identifiable by POCSI or LUS, these lesions were apparent on DL even before ICG-FI. Therefore, its utility as an intraoperative diagnostic modality is limited at the dosage and timing used in the study. We believe that rather than a diagnostic tool, it has more potential for a dynamic use in guiding the resection of superficial lesions and delineating segmental/lobar anatomy.

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Section: Discussionmentioning

confidence: 97%

A comparison of indocyanine green fluorescence and laparoscopic ultrasound for detection of liver tumors

Köse

Kahramangil

Aydın

et al. 2020

HPB

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“…A diagnostic aid to help the clinician to delineate surgical margins would be very useful [7,10]. Recent trials on using tissue auto-fluorescence as a sensitive method to detect surgical margins have been described in various tumors such as breast cancer (BC) and have shown accurate results [11,12]. Poh et al [13] in Canada has used a similar device to detect field change around squamous cell carcinoma and found a positive correlation between loss of heterozygosity and fluorescence visualization loss.…”

Section: Introductionmentioning

confidence: 99%

Oral ID® as an adjunctive tool for surgical margin assessment in patients with oral squamous cell carcinoma: a comparative study

MOHAMED¹,

MOHAMMED²,

SULAIMAN³

2021

Braz. Dent. Sci.

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Objective: The condition of the resected margin in oral squamous cell carcinoma continues to be an important prognostic factor; the use of optic technology could help surgeons in determining the margin status at real time. This study aims to evaluate Oral ID, a hand held device that uses the principal of auto-fluorescence to determine surgical safe margins in patients with oral squamous cell carcinoma, and to compare the results with those of the conventional 1 cm margin method. Material and Methods: This study was a descriptive, comparative analytical study carried out at

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Chylothorax

McAnulty¹

2023

Small Animal Soft Tissue Surgery

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Fluorescence Imaging for Surgeons

Cited by 17 publications

References 10 publications

A comparison of indocyanine green fluorescence and laparoscopic ultrasound for detection of liver tumors

A comparison of indocyanine green fluorescence and laparoscopic ultrasound for detection of liver tumors

Oral ID® as an adjunctive tool for surgical margin assessment in patients with oral squamous cell carcinoma: a comparative study

Chylothorax

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