Fluorescence enhancement by hollow plasmonic assembly and its biosensing application

Plasmon-Coupled Directional Emission from Soluplus-Mediated AgAu Nanoparticles for Attomolar Sensing Using a Smartphone

“…Furthermore, recently, gold nanocages and nanoshells have been reported in the SPCE platform to understand the effects from hollow plasmonic nanostructures toward dequenching the emission. The strong plasmonic coupling interactions between the hollow nanoparticles and the SPPs of metallic thin films provide a superior wavelength match, and an augmented EM field with a new radiation channel for significantly enhancing the sensitivity of biomolecules in the nanogap region. , These techniques were employed using quantum dots and gold nanoarchitectures to realize simultaneous enhancement in multiple wavelengths in the SPCE platform, amenable for multiplexed detection and imaging of different analytes . In this regard, we emphasize the utility of multiple hotspots supported by such anisotropic nanostructures toward dequenching the emission in SPCE.…”

“…54,55 These techniques were employed using quantum dots and gold nanoarchitectures to realize simultaneous enhancement in multiple wavelengths in the SPCE platform, amenable for multiplexed detection and imaging of different analytes. 55 In this regard, we emphasize the utility of multiple hotspots supported by such anisotropic nanostructures toward dequenching the emission in SPCE. The experimentally observed 1200-fold emission enhancements can hence be elucidated by taking into consideration all the abovementioned points that give rise to coherent and collective plasmonic resonances aiding in multiple hotspots.…”

Amplified Fluorescence by Hollow-Porous Plasmonic Assembly: A New Observation and Its Application in Multiwavelength Simultaneous Detection

“…As important spectral technologies, fluorescence-based techniques have been widely used in all kinds of analysis and detection, but insufficient sensitivity limits their further development. − It has been shown that the radiation decay rate and the distribution of radiation energy of fluorophores can be changed when they are placed on a metal surface or a metal surface with nanostructures, which enables the increase of sensitivity. A new technique, namely, surface plasmon coupled emission (SPCE), in which directional and enhanced radiation is produced by the interaction between an excited fluorophore in the near-field (20–200 nm) of a continuous metallic surface and surface plasmons (SPs), − has been developed and demonstrated to be useful in biochemical detection − and imaging , due to its distance dependence and wavelength resolution.…”

“…Under suitable conditions, the coupling between them happens, which can be accompanied by significant EM field enhancement. , The application of hollow-porous NPs in SPCE has not been reported, and this introduction of AuNCs is expected to create a new plasmonic enhancement system. When the natural plasmonic properties of AuNC are considered, a more remarkable enhancement for SPCE should be realized compared with the enhancement by other special-shaped NPs, such as nanoprisms, nanoshells, nanocubes, and nanostars. ,,, This paper explores a novel strategy to enhance the SPCE signal as well as overcome signal quenching, and this fantastic process is attributed to the superior wavelength match, enhanced EM field, and new radiation channel and process induced by the modification of AuNCs on a gold substrate. The strategy we propose here can increase the sensitivity of SPCE and enable the establishment of a new optimal plasmonic enhancement system.…”

“…The mixed NPs consisted of various ratios of gold nanoshells (AuNSs) and AuNCs, and the multiwavelength signal was generated from the mixed QD solution with different emission wavelengths. The SPCE enhancement of AuNSs has been investigated . The SPCE spectra that were collected from the optimal emission angles (Figure S18a) for different wavelengths without NP modification are shown in Figure S18b.…”