Fluorescence devices for the detection of dental caries

Macey, Richard; Walsh, Tanya; Riley, Philip; Glenny, Anne‐Marie; Worthington, Helen V; Fee, Patrick A; Clarkson, Jan E; Ricketts, David

doi:10.1002/14651858.cd013811

Cited by 21 publications

(18 citation statements)

References 203 publications

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“…Nevertheless, even if welldefined eligibility criteria were described in a few RCTs (Hashem et al, 2015(Hashem et al, , 2019Kundzina et al, 2017), the exact depth of the carious lesion is generally determined during the treatment, which impedes proper randomization pre-operatively. Additionally, caries removal might be very subjective and practitioner-dependent if no additional caries detection tools and magnification are used (Macey et al, 2020;Steier et al, 2021).…”

Section: Intra-coronal Materialsmentioning

confidence: 99%

Present status and future directions: Hydraulic materials for endodontic use

Camilleri

Atmeh

et al. 2022

Int Endodontic J

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Background Hydraulic materials are used in Endodontics due to their hydration characteristics namely the formation of calcium hydroxide when mixing with water and also because of their hydraulic properties. These materials are presented in various consistencies and delivery methods. They are composed primarily of tricalcium and dicalcium silicate, and also include a radiopacifier, additives and an aqueous or a non‐aqueous vehicle. Only materials whose primary reaction is with water can be classified as hydraulic. Objectives Review of the classification of hydraulic materials by Camilleri and the literature pertaining to specific uses of hydraulic cements in endodontics namely intra‐coronal, intra‐radicular and extra‐radicular. Review of the literature on the material properties linked to specific uses providing the current status of these materials after which future trends and gaps in knowledge could be identified. Methods The literature was reviewed using PUBMED, and for each clinical use, the in vitro properties such as physical, chemical, biological and antimicrobial characteristics and clinical data were extracted and evaluated. Results A large number of publications were retrieved for each clinical use and these were grouped depending on the property type being investigated. Conclusions The hydraulic cements have made a difference in clinical outcomes. The main shortcoming is the poor testing methodologies employed which provide very limited information and also inhibits adequate clinical translation. Furthermore, the clinical protocols need to be updated to enable the materials to be employed effectively.

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Section: Intra-coronal Materialsmentioning

confidence: 99%

Present status and future directions: Hydraulic materials for endodontic use

Camilleri

Atmeh

et al. 2022

Int Endodontic J

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“…The specified meta-analysis consisted of in vitro-weighted publications. [43]. Until a more accurate reference standard is developed which prioritizes in vivo safe use, the evaluation of such studies will be possible with the application of micro-CT after extraction, as in this study.…”

Section: Discussionmentioning

confidence: 99%

“…Until a more accurate reference standard is developed which prioritizes in vivo safe use, the evaluation of such studies will be possible with the application of micro-CT after extraction, as in this study. It is thought that with the developments in 3D technology, concerns about the intraoral applicability of the reference standard will become absolete [43].…”

Section: Discussionmentioning

confidence: 99%

Clinical Performance of Diagnostic Methods in Third Molar Teeth with Early Occlusal Caries

et al. 2023

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The aim of this study was to compare the diagnostic performance of clinical visual examination (ICDAS II), digital periapical radiography (PR), near infrared light transillumination (NIR-LT), and laser fluorescence (LF) to microcomputed tomography (Micro-CT) which is the reference standard for the detection of non-cavitated occlusal enamel and dentin caries in third molar teeth. Potential participants were consecutively recruited. In this prospective study, 101 third molars of 101 patients were examined; the molars had non-cavitated occlusal caries which required extraction. ICDAS II, PR, NIR-LT and LF examinations were carried out by two blinded examiners. Reference standard was determined by micro-CT imaging seven days after extraction. Accuracy rate, sensitivity, specificity, predictive values and areas under receiver operating characteristic (ROC) curves (Az) were statistically analyzed. Nonparametric variables were subjected to the Kruskal–Wallis Test. Significance level was set as p < 0.05. NIR-LT had the highest sensitivity (99.67–99.67%) and accuracy (78.22–77.23%) for the determination of occlusal enamel caries according to examiners 1 and 2, respectively. LF method had the highest sensitivity (70.83–54.17%) and accuracy (66.34–59.41%) for determining occlusal dentin caries according to examiners 1 and 2, respectively. The ROC curve (Az) value ranged between 0.524 and 0.726 for the different methods tested. Most effective methods for the diagnosis of occlusal enamel and dentin caries were determined to be NIR-LT and LF pen methods, respectively. The present prospective clinical study showed that NIR-LT and LF-Pen were a reliable modality for the detection of occlusal enamel and dentin caries without ionizing radiation.

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“…We identified 5 Cochrane DTA systematic reviews meeting the following criteria ( Macey et al 2020 ; Macey, Walsh, Riley, Glenny, Worthington, Clarkson, et al 2021 ; Macey, Walsh, Riley, Glenny, Worthington, O’Malley, et al 2021 ; Macey, Walsh, Riley, Hogan, et al 2021 ; Walsh et al 2021 ).…”

Section: Methodsmentioning

confidence: 99%

“…To inform the detection and diagnosis of early caries, we recently authored a suite of Cochrane diagnostic test accuracy (DTA) reviews of 1) fluorescence, 2) visual or visual-tactile examination according to detailed criteria, 3) radiographic imaging and cone beam computed tomography (CBCT), 4) optical coherence tomography and transillumination, and 5) electrical conductance or impedance ( Macey et al 2020 ; Macey, Walsh, Riley, Glenny, Worthington, Clarkson, et al 2021 ; Macey, Walsh, Riley, Glenny, Worthington, O’Malley, et al 2021 ; Macey, Walsh, Riley, Hogan, et al 2021 ; Walsh et al 2021 ). These were published as separate reviews, so only naïve comparisons of the technologies could be made.…”

Section: Introductionmentioning

confidence: 99%

Enamel Caries Detection and Diagnosis: An Analysis of Systematic Reviews

et al. 2021

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Detection and diagnosis of caries—typically undertaken through a visual-tactile examination, often with supporting radiographic investigations—is commonly regarded as being broadly effective at detecting caries that has progressed into dentine and reached a threshold where restoration is necessary. With earlier detection comes an opportunity to stabilize disease or even remineralize the tooth surface, maximizing retention of tooth tissue and preventing a lifelong cycle of restoration. We undertook a formal comparative analysis of the diagnostic accuracy of different technologies to detect and inform the diagnosis of early caries using published Cochrane systematic reviews. Forming the basis of our comparative analysis were 5 Cochrane diagnostic test accuracy systematic reviews evaluating fluorescence, visual or visual-tactile classification systems, imaging, transillumination and optical coherence tomography, and electrical conductance or impedance technologies. Acceptable reference standards included histology, operative exploration, or enhanced visual assessment (with or without tooth separation) as appropriate. We conducted 2 analyses based on study design: a fully within-study, within-person analysis and a network meta-analysis based on direct and indirect comparisons. Nineteen studies provided data for the fully within-person analysis and 64 studies for the network meta-analysis. Of the 5 technologies evaluated, the greatest pairwise differences were observed in summary sensitivity points for imaging and all other technologies, but summary specificity points were broadly similar. For both analyses, the wide 95% prediction intervals indicated the uncertainty of future diagnostic accuracy across all technologies. The certainty of evidence was low, downgraded for study limitations, inconsistency, and indirectness. Summary estimates of diagnostic accuracy for most technologies indicate that the degree of certitude with which a decision is made regarding the presence or absence of disease may be enhanced with the use of such devices. However, given the broad prediction intervals, it is challenging to predict their accuracy in any future “real world” context.

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Fluorescence devices for the detection of dental caries

Abstract: Fluorescence devices for the detection of dental caries.

Cited by 21 publications

References 203 publications

Present status and future directions: Hydraulic materials for endodontic use

Present status and future directions: Hydraulic materials for endodontic use

Clinical Performance of Diagnostic Methods in Third Molar Teeth with Early Occlusal Caries

Enamel Caries Detection and Diagnosis: An Analysis of Systematic Reviews

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