Fluorescence Chemosensors for Chemical Warfare Agent Mimic Diethylcyanophosphonate Via Co²⁺ -Naphthalimide Based Nanoaggregate in Aqueous Medium

Abstract

Two new Naphthalimide based dipodal receptors K1 and K2 has been synthesized and selectively formed upon complexation with cobalt ion. Further, these cobalt complexes (K1.Co 2 + and K2.Co 2 + ) were fabricated to nanoaggregate in aqueous medium. The stability of these nanoaggregates was established with DLS, TEM, AFM and emission spectroscopy. The nanoaggregates N1-N2 were utilized to selectively sensing of diethylcyanophosphonate in aqueous medium. The nanoaggre-gate N1 and N2 exhibit 2 fold enhancement in the emission spectrum in presence of Diethylcyanophosphonate (DECP) which is due to rigidity induced fluorescent enhancement. The detection limit to be achieved for DECP is 21 nM in aqueous medium. Additionally, the solution coated filter paper strip of nanoaggregate N1 can detect DECP, thus providing very simple and low coast sensing kit for DECP.

Fluorescent probes for the detection of chemical warfare agents

“…Raj et al designed and synthesized two Co 2+ -naphthalimide-based fluorescent probes, K1ÁCo 2+ (122) and K2ÁCo 2+ (123). 139 Both K1ÁCo 2+ and K2ÁCo 2+ exhibited a 2-fold fluorescence enhancement upon contact with DECP, and K1ÁCo 2+ had an LOD for DECP of 21 nM. More recently, this group reported a series of dimethyltin(IV) compounds (124)(125)(126)(127) for DCP detection.…”