Abstract:Neutralizing antibodies induced by vaccination or natural infection play a critically important role in protection against the viral diseases. In general, neutralization of the viral infection occurs via two major pathways: pre- and post-attachment modes, the first being the most important for such infections as influenza and polio, the latter being significant for filoviruses. Neutralizing capacity of antibodies is typically evaluated by virus neutralization assays that assess reduction of viral infectivity t… Show more
“… 21 To further enhance fully human IgG production with human IgG1 subclass dominancy in Tc bovine, the human IGHM constant region and key regulatory sequences on the HAC were optimized. 21 , 41 …”
“… 21 To further enhance fully human IgG production with human IgG1 subclass dominancy in Tc bovine, the human IGHM constant region and key regulatory sequences on the HAC were optimized. 21 , 41 …”
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