Fluorescein Angiography in Intracranial Aneurysm Surgery: A Helpful Method to Evaluate the Security of Clipping and Observe Blood Flow

Variational Method for Estimating the Dipole Moment in the Second Excited State of Fluorescein Molecule from its Electronic UV Absorption Spectra

“…(9) The next condition is necessary to have real values for excited state dipole moment: ∆ ≥ 0 for ϕ ≤ 79.02°. (10) It results that the angle ϕ between the molecular dipole moments in the electronic states of fluorescein must be smaller than 79°. Considering the value 7.94 D for the ground state dipole moment and 66.33 Å 3 for the ground state polarizability of fluorescein, one obtains the data from Table 8 for step by step variation of ϕ with 10°.…”

“…Thus, fluorescein fluorescence technology is a valuable tool in the surgical * email: ddorohoi@uaic.ro management of neoplastic and vascular lesions [9]. By using a microscope-integrated fluorescence module, this technique allows performing intraoperative angiography to guide microsurgical management of aneurysms and arteriovenous malformations, as well as the maximization of tumor resection [10]. A comprehensive review on the fluorescein-guided surgery of malignant gliomas can be found in [11].…”

Preventing Rupture: Clipping of Unruptured Intracranial Aneurysms

“…The bypass techniques are currently used in the management of more complex giant aneurysms, however with less satisfactory outcomes than the standard surgical approaches for smaller aneurysms [5,17]. A more recent advancement has been the introduction of intraoperative videoangiography by means of fluorescent dyes such as fluorescein sodium or indocyanine green [18]. Charles Wrobel first described this method in 1994 for real-time testing of aneurysmal obliteration and the patency of adjacent arteries [5,19].…”

“…Charles Wrobel first described this method in 1994 for real-time testing of aneurysmal obliteration and the patency of adjacent arteries [5,19]. This tool renders intraoperative catheter-based angiography or Doppler ultrasonography obsolete in certain cases and allows repositioning of inconveniently placed clips before the onset of permanent damage [5,[18][19][20]. Other contemporary innovations include the endoscopic endonasal approaches in order to clip skull base aneurysms; however, this technique awaits further validation [5,[21][22][23].…”

Ensayo Pictórico: Control imagenológico de aneurismas tratados ¿Qué examen elegir?

“…En presencia de múltiples clips, clips orientados paralelos al vaso parental o en el plano de adqui-sición, su rendimiento disminuye 6 La clasificación de Sindou establece cinco categorías en cuanto a la presencia de aneurisma residual; los grados I y II presentan respectivamente opacificación menor a 50% y mayor a 50% del cuello del aneurisma; los grados III, IV y V adicionalmente al cuello remanente presentan opacificación de un lóbulo, de menos de 75% o más de 75% del saco aneurismático respectivamente7. El control durante la cirugía puede ser realizado con ASD, angiografía por fluorescencia con fluoresceína o indocianina 8 . Los remanentes con saco aneurismático (grados III, IV y V) son susceptibles a retratamiento, ya sea por vía quirúrgica o endovascular 9 .…”