Fluid–structure interaction modeling of blood flow and cerebral aneurysm: Significance of artery and aneurysm shapes

Computational vascular fluid–structure interaction: methodology and application to cerebral aneurysms

“…6, the models are superposed in the configurations corresponding to low diastole and peak systole for better visualization of the relative displacement results. The relative displacement predicted is quite modest and is in good agreement with the observed vessel motions during aneurysm surgery in the clinical practice of one of the authors and predicted in computations by other researchers (see, e.g., Tezduyar et al 2007;Torii et al 2008Torii et al , 2009). Figure 7 shows a distribution of principal in-plane strain (Green-Lagrange strain measure is employed) at peak systole.…”

“…The Arbitrary Lagrangian-Eulerian (ALE) formulation is used, which is a widely used approach for vascular blood flow applications Formaggia et al 2001;Gerbeau et al 2005;Fernández et al 2008). Alternatively, one can apply the space-time methodology Torii et al 2008Torii et al , 2009, which leads to better time accuracy, yet somewhat higher computational expense per time step.…”

“…Numerous advances in the simulation technology were proposed, such as imposition of physiologically-realistic outflow boundary conditions (Formaggia et al 2001;Lagana et al 2002;VignonClementel et al 2006), simulation of stenting technology in the context of cerebral aneurysms (Appanaboyina et al 2009) and coronary arteries (Zunino et al 2009), optimization of cardiovascular geometries for surgical treatment (Marsden et al 2008), inclusion of the effects of wall elasticity Bazilevs et al 2006Bazilevs et al , 2008Tezduyar et al 2007;Torii et al 2008Torii et al , 2009, and growth and remodeling (Figueroa et al 2009) in the simulations. Nowadays, the state-of-the-art in computational hemodynamics involves fully coupled fluid-structure patient-specific simulations of large portions of the human cardiovascular system.…”

“…Despite its modeling shortcomings, pure CFD remains the predominant modeling approach for vascular blood flow, and, in particular, for computation of aneurysm flows. Notable exceptions include the work of (Takizawa et al 2010a,b;Torii et al 2006aTorii et al ,b, 2007Torii et al , 2008Torii et al , 2009) on cerebral aneurysms and the work of (Wolters et al 2005;Scotti and Finol 2007;Rissland et al 2009) on aortic abdominal aneurysms. This paper likewise focuses on developing and using advanced FSI computational techniques to assess the risk of rupture for cerebral aneurysms in individual patients.…”

Fluid-Structure Simulations and Benchmarking of Artery Aneurysms Under Pulsatile Blood Flow

“…There have been several patient-specific FSI simulations of aneurysms, involving both intracranial aneurysms ( [7], [24], [25], [26], [28]) and AAA, namely abdominal aortic aneurysms ( [12], [31], [18], [22]). Numerous advances in the simulation technology were proposed, but the majority of them involved only computational fluid dynamics (CFD).…”