Fluid Resuscitation in Tactical Combat Casualty Care; TCCC Guidelines Change 21-01. 4 November 2021

Deaton, Travis G; Auten, Jonathan D.; Betzold, Richard; Butler, Frank K.; Byrne, Terence; Andrew, P; Donham, Benjamin; DuBose, Joseph J.; Fisher, Andrew D; Hancock, J. F.; Jourdain, V; Knight, Ryan M; Littlejohn, Lanny F.; Martin, Matthew J.; Toland, Kevin; Drew, Brendon

doi:10.55460/jylu-4oz8

Cited by 16 publications

(17 citation statements)

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“…At this time, the use of cold-stored whole blood is considered a best practice by the US military, in adult trauma centers in the United States, and internationally. 43,[54][55][56] The benefits and risks of LTOWB compared with component therapy are summarized in Table 1. 45,50,51,53,57,58 Current data support that LTOWB is a safe, efficient, and feasible tool in pediatric trauma resuscitation and may also improve clinical outcomes.…”

Section: Whole Bloodmentioning

confidence: 99%

Resuscitative practices and the use of low-titer group O whole blood in pediatric trauma

Morgan

Leeper

Yazer

et al. 2022

J Trauma Acute Care Surg

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Increasing rates of penetrating trauma in the United States makes rapid identification of hemorrhagic shock, coagulopathy, and early initiation of balanced resuscitation in injured children of critical importance. Hemorrhagic shock begins early after injury and can be challenging to identify in children, as hypotension is a late sign that a child is on the verge of circulatory collapse and should be aggressively resuscitated. Recent data support shifting away from crystalloid and toward early resuscitation with blood products because of worse coagulopathy and clinical outcomes in injured patients resuscitated with crystalloid. Multicenter studies have found improved survival in injured children who receive balanced resuscitation with higher fresh frozen plasma: red blood cell ratios. Whole blood is an efficient way to achieve balanced resuscitation in critically injured children with limited intravenous access and decreased exposure to multiple donors. Administration of cold-stored, low-titer O-negative whole blood (LTOWB) appears to be safe in adults and children and may be associated with improved survival in children with life-threatening hemorrhage. Many pediatric centers use RhD-negative LTOWB for all female children because of the risk of hemolytic disease of the fetus and newborn (0-6%); however. there is a scarcity of LTOWB compared with the demand. Low risks of hemolytic disease of the fetus and newborn affecting a future pregnancy must be weighed against high mortality rates in delayed blood product administration in children in hemorrhagic shock. Survey studies involving key stakeholder's opinions on pediatric blood transfusion practices are underway. Existing pediatric-specific literature on trauma resuscitation is often limited and underpowered; multicenter prospective studies are urgently needed to define optimal resuscitation products and practices in injured children in an era of increasing penetrating trauma.

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Section: Whole Bloodmentioning

confidence: 99%

Resuscitative practices and the use of low-titer group O whole blood in pediatric trauma

Morgan

Leeper

Yazer

et al. 2022

J Trauma Acute Care Surg

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“…There is no objective method to measure this outcome. THOR Network attendees have acknowledged that the THOR Network symposia and THOR 100 papers have significantly contributed to the implementation of both fresh and stored low titer group O whole blood in many military programs 16 and low titer group O whole blood programs in civilian programs 17 . Other topics focused on at THOR Network symposia and supplements include cold storage of platelets, becoming less permissive with hypotension, presurgical repair, avoiding intubation of a patient in hemorrhagic shock if possible, and if not, providing adequate blood‐based resuscitation prior to intubation.…”

Section: Discussionmentioning

confidence: 99%

The publication impact of the first 100 THOR Network publications by bibliometric and social network analyses

Woolley

Stubbs

Sprague³

et al. 2022

Transfusion

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Background A specialized international multidisciplinary group of investigators wanted to determine the performance and impact of publications presented at an annual conference over a 6 year period. Specifically, the group wanted to know if the influence of the conference publications extended beyond conference publication authors and attendees. Bibliometric methods and network analyses were used to evaluate the performance and impact of 100 peer‐reviewed publications presented at the Trauma Hemostasis and Oxygenation Research (THOR) Network Remote Damage Control Resuscitation (RCDR) Symposia from 2012 to 2017 (published 2013–2018). Further analysis was performed on the affiliations of conference attendees who attended from the years of 2012 to 2017. Study Design and Methods This project used normative and relative bibliometric measures and social network analysis to evaluate the performance and impact of 100 peer‐reviewed publications presented at the Trauma Hemostasis and Oxygenation Research (THOR) Network RDCR Symposia from 2012 to 2017. Publication and citation data were from Elsevier Scopus, a bibliographic citation database. Metrics from Elsevier SciVal were selected for the project to normalize for group size, year of publication, and document type. A six‐year period of publications presented at the Symposia, published from 2013 to 2018, was selected for analysis. The publication and citation data were further analyzed using Elsevier SciVal and the iCite database from the National Institutes of Health Office of Portfolio Analysis. Sci2, VOSviewer, and Gephi were used for social network analyses and visualization. Results The 100 publications presented at the Trauma Hemostasis and Oxygenation Research (THOR) Network Remote Damage Control Resuscitation (RCDR) Symposia from 2012 to 2017 demonstrate reach and influence beyond the authors of the THOR publications or the THOR attendees. Citations to the THOR publications were published in 10 languages and 313 unique journals, with author affiliations from 62 countries. Citation metrics for the THOR publications exceed global averages with 65% of the THOR publications being in the 25% citation percentiles. When benchmarking the THOR publications using six homogenous comparator groups, the THOR publications demonstrate higher citation metrics than any of the comparator groups with more citations per publication, a higher average of cited publications, higher FWCI and outputs in the top citation percentiles among the six groups. The Office of Portfolio Analysis (OPA) iCite database was used to calculate potential to translate for the THOR publications with 57 of the THOR publications cited by clinical articles with an average approximate potential to translate score of 65.3%. Conclusions The value of international groups with sharing of research and knowledge are instrumental in enhancing the uptake for best practices for in medicine and treatment of hemorrhagic shock resuscitation. The use of bibliometric methods and network analyses, along with benchmar...

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“…Permissive hypotension has long been suggested as a potentially valuable component of a hemostatic strategy in that keeping SBP as low as 80 mmHg would allow adequate perfusion while reducing the risk of "popping the clot" and re-inducing lifethreatening hemorrhage This recommendation has recently been modified to target a SBP range of 90-110 mmHg (>110 mmHg in patients with traumatic brain injury (TBI)) given the relationship between increased SBP and lower mortality. 39 However, the common doctrine of the use of mental status and ability to palpate a radial, carotid, or femoral pulse as an indication of hypotension is fraught with problems. 40 Noninvasive oscillometric-based blood pressure monitoring traditionally used in the prehospital and emergency care setting are well known to differ significantly from invasive arterial blood pressure monitors.…”

Section: Adjuncts To Assist Your Decision On When To Initiate a Preho...mentioning

confidence: 99%

Tips, tricks, and thoughts on the future of prehospital blood transfusions

et al. 2022

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Fluid Resuscitation in Tactical Combat Casualty Care; TCCC Guidelines Change 21-01. 4 November 2021

Cited by 16 publications

References 0 publications

Resuscitative practices and the use of low-titer group O whole blood in pediatric trauma

Resuscitative practices and the use of low-titer group O whole blood in pediatric trauma

The publication impact of the first 100 THOR Network publications by bibliometric and social network analyses

Tips, tricks, and thoughts on the future of prehospital blood transfusions

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