Fluid Management in Dengue Critical Phase: Which, When, How Much?

Abstract

Dengue is a very common viral infection in tropical zones, it is transmitted by vectors to humans by mosquito bites of the genre: Aedes. Oriental Mediterranean, Americas, Southeast Asia, Pacific, and Africa are all known as endemic zones for dengue. The treatment of severe dengue is based on the administration of intravenous fluids (IVF) and the management of complications. The mainstay of the management is the meticulous administration of fluids to ensure adequate intravascular volume to restore vasculopathy, watching carefully for overload risk. We carried out a state of the art on fluid-therapy during the critical phase of dengue, including the type (crystalloids versus colloids, hypotonic and hypertonic solutions), volume to infuse and duration of therapy from the most recent publications. This is an area where urgent research is needed.