Fluid bed granulations in microscale fluid bed powder processor (MFP)

Fluidization technologies: Aerodynamic principles and process engineering

“…With the importance of process analytical technology, the on‐line and at‐line measurements using suitable probes have been incorporated in fluid‐bed granulation 82. Experiments of fluid‐bed granulations at microscale levels and small scale batch coatings have been studied 83, 84…”

Study of fluid bed granulation processes with new technology approaches

“…It leads to the production of high-quality, low dust and low attrition solids by modifying their physical properties (size, shape, density, porosity) (Banks and Aulton, 1991; Radichkov et al, 2006; Sherrington and Oliver, 1981;Pietch, 1984). Both the spraying and drying of the agglomerates are carried out in a single piece of equipment offering several advantages over other multi-step granulation and drying processes (Smith, 1980;Kivikero et al, 2007;Närvänen, 2008;Petrović et al, 2011). This results in the reduction of the manufacturing processes and manufacturing time, which benefits the Good Manufacturing Practice (GMP) requirements (Gao et al, 2002).…”