Fluconazole treatment without catheter removal in Candida albicans peritonitis complicating peritoneal dialysis

Corbella, Xavier; Sirvent, Josep Maria; Carratalà, Jordi

doi:10.1016/0002-9343(91)90560-k

Cited by 6 publications

(4 citation statements)

References 3 publications

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“…In 1989, Levine et al reported two cases of FP successfully returned to CAPD after treatment with fluconazole and catheter removal (19). Isolated case reports also exist describing successful treatment with fluconazole alone without catheter removal (20,21). However, the overall cure rate without catheter removal in other, larger series was still very low (8%, Table 4) (3,6,8,10,17,22,23).…”

Section: Treatment and Outcomementioning

confidence: 99%

Fungal Peritonitis -Current Status 1998

Chan

Lui

et al. 1999

Perit Dial Int

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Section: Treatment and Outcomementioning

confidence: 99%

Fungal Peritonitis -Current Status 1998

Chan

Lui

et al. 1999

Perit Dial Int

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“…Nur in frühen Phasen der Erkrankung kann bei fehlenden klinischen Zeichen (niedriges CRP, Leukozytose <10.000, Temperatur <38°) und stabilen Kreislaufverhältnissen der Peritonealdialysekatheter belassen werden. Persistieren die Pilze, muss der (Dialyse)‐Katheter entfernt werden 23, 24 . Bei deutlichem Peritonismus und entsprechender Klinik sollte initial eine l.aparoskopie des Abdomens vorgenommen werden, um eine tiefe peritoneale Mykose durch Biopsie auszuschließen.…”

Section: Katheter‐assozierte Pilzperitonitisunclassified

“…Persistieren die Pilze, muss der (Dialyse)-Katheter entfernt werden. 23,24 Bei deutlichem Peritonismus und entsprechender Klinik sollte initial eine l.aparoskopie des Abdomens vorgenommen werden, um eine tiefe peritoneale Mykose durch Biopsie auszuschließen. Dieses ist ein einfaches, den Patienten wenig belastendes Verfahren, das eine hohe diagnostische Sicherheit bietet.…”

Section: Katheter-assozierte Pilzperitonitisunclassified

Intraabdominelle Pilzinfektionen

Boos

Kujath²,

Hp³

2005

Mycoses

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The incidence of invasive mycoses in patients undergoing abdominal surgery amounts to approximately 8% and shows an upward trend in epidemiological studies. The lethality of these systemic mycoses, which are mostly based on Candida infections constitutes up to 60%. The development of a sytemic mycosis is marked by exogenic, endogenic and iatrogenic risk factors and typically displays tissue invasion after an initial fungal contamination or systemic dissemination via fungal sepsis. Fungal peritonitis is generally a monoinfection with Candida spp., where Candida albicans outweighs in 70% of cases. Aspergillus spp. are only detected abdominally in rare cases. The histological verification of a fungal invasion is regarded as proof of the existence of an invasive mycosis, but typical macroscopic findings with corresponding cultural findings can also confirm the diagnosis. Systemic mycosis requires an early initiation of a consistent antimycotic therapy as well as definitive surgical eradication of the focus in order to reduce high lethal rate. Resistances or incorrect dosages can be validated objectively by means of histological monitoring of the antimycotic therapy, thus affording early recognition of the need to change the substance class.

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“…Neben der frühzeitigen antimykotischen Therapie ist die Entfernung des Dialysekatheters erforderlich 14 . Bei frühen Phasen der Erkrankung ohne Anzeichen einer Sepsis kann der Peritonealkatheter belassen und eine intraabdominelle Behandlung mit Amphotericin B oder Fluconazol durchgeführt werden 15 …”

Section: Ergebnisse Und Diskussionunclassified

Schwere, sklerosierende Candida‐peritonitis nach CAPD – ein glücklicher Verlauf

Hennings¹,

Bouchard

Klempien

et al. 2005

Mycoses

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Continuous ambulatory peritoneal dialysis (CAPD) is a widespread method of treatment used in approximately 10% of all patients suffering from terminal renal insufficiency. The main problem of this procedure is the increased risk of peritoneal infection. The incidence of such a peritonitis is quoted at one episode per 13-18.4 months of treatment. Candida peritonitis is a particularly severe form of CAPD peritonitis. This is a nosocomial infection with a high lethality rate of about 60%. The incidence of Candida peritonitis in CAPD patients amounts to approximately 5% of all intraabdominal infections and is on the increase. The authors describe a severe case of Candida peritonitis in a patient on CAPD. The therapeutic concept of this severe illness is illustrated.

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Fluconazole treatment without catheter removal in Candida albicans peritonitis complicating peritoneal dialysis

Cited by 6 publications

References 3 publications

Fungal Peritonitis -Current Status 1998

Fungal Peritonitis -Current Status 1998

Intraabdominelle Pilzinfektionen

Schwere, sklerosierende Candida‐peritonitis nach CAPD – ein glücklicher Verlauf

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