Flow-volume Curves and Breathing Patterns during Exercise in Patients with Obstructive Lung Disease

Grimby, Gunnar; Stiksa, J

doi:10.3109/00365517009046210

Cited by 55 publications

(34 citation statements)

References 13 publications

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“…These workers suggested that this phenomenon might reflect large time-constant discrepancies between serially arranged elements. Finally, the normal subjects during exercise either maintained or lowered their FRC, whereas the patients tended to increase FRC during exercise, an observation also stressed by Grimby and Stiksa (10).…”

Section: Discussionmentioning

confidence: 51%

See 1 more Smart Citation

Ventilatory mechanics and expiratory flow limitation during exercise in patients with obstructive lung disease

Potter¹,

Ólafsson²,

Hyatt³

1971

J. Clin. Invest.

204

142

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Section: Discussionmentioning

confidence: 51%

“…A number of studies have described various aspects of lung mechanics during exercise in subjects with chronic obstructive lung disease (COLD) (3)(4)(5)(6)(7)(8)(9)(10). However (Table I).…”

Section: Introductionmentioning

confidence: 99%

Ventilatory mechanics and expiratory flow limitation during exercise in patients with obstructive lung disease

Potter¹,

Ólafsson²,

Hyatt³

1971

J. Clin. Invest.

204

142

View full text Add to dashboard Cite

“…In these circumstances, expiratory flow cannot increase, irrespective of the activity of the expiratory muscles [3,4]. Greater expiratory flow can only be achieved by increasing the operating lung volume, shifting end-expiratory lung volume towards the total lung capacity [5]. Hyperinflation of the lungs may improve airflow, but it comes at the cost of increased inspiratory work and may also impair inspiratory muscle function [6].…”

Section: Introductionmentioning

confidence: 99%

Variability of within-breath reactance in COPD patients and its association with dyspnoea

et al. 2014

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The forced oscillation technique can identify expiratory flow limitation (EFL) when a large difference in inspiratory and expiratory reactance (ΔXrs) occurs. However, flow limitation can vary from breath to breath, and so we compared a multiple-breath ΔXrs approach to the traditional breath-by-breath assessment of EFL. We investigated the within-and between-day reproducibility and the factors that affect the size of ΔXrs when used as a continuous measurement over multiple breaths. In addition, we examined how multiple-breath ΔXrs relates to the sensation of breathlessness.425 moderate to very severe chronic obstructive pulmonary disease (COPD) patients and 229 controls were included. Spirometry and impedance measurements were performed on a MasterScope CT Impulse Oscillation System.Median ΔXrs approached zero in healthy controls with little variation between measurements. COPD patients generally had higher ΔXrs and higher variability. The COPD patients with ΔXrs >0.1 kPa·Lwere prone to be more breathless and had a higher modified Medical Research Council dyspnoea scale score. In controls, the 95th percentile of ΔXrs was as low as 0.07 kPa·L −1 ·s −1 . We describe a new method to assess EFL at a patient level and propose a cut-off, mean ΔXrs >0.1 kPa·L −1 ·s −1 , as a way to identify COPD patients who are more likely to report dyspnoea. @ERSpublications Within-breath reactance in COPD correlates with dyspnoea and adds information beyond that of spirometry alone

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“…however, conventional spirometric techniques, such as air flow measurements, do not always detect this hyperinflation. therefore, the inspiratory capacity (IC) maneuver has been used to monitor exercise-induced Dh [3][4][5] . Since total lung capacity (tlC) does not change with exercise in CopD patients, changes in IC reflect changes in functional residual capacity (FRC) 6 .…”

Section: Introductionmentioning

confidence: 99%

Análise da hiperinsuflação pulmonar dinâmica (HD) após atividade de vida diária em pacientes com doença pulmonar obstrutiva crônica

Pessoa

Parreira

Lorenzo

et al. 2007

Rev. bras. fisioter.

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Introduction: Dynamic hyperinflation (Dh) is one of the ventilatory mechanisms that may contribute towards limiting the activities of daily living (ADls) in patients with chronic obstructive pulmonary disease (CopD). the objectives of this study were to evaluate the presence of Dh, by means of inspiratory capacity (IC), IC / total lung capacity (tlC) ratio and by the sensation of dyspnea, following an ADl performed using the upper limbs. method: the participants were 32 individuals aged 54 to 87 years (69.4 ± 7.4) who presented moderate-to-severe CopD. the patients selected underwent pulmonary function tests, spirometry and whole-body plethysmography. For the spirometric and pulmonary volume maneuvers, a conventional system was used (vmax22 Autobox). the IC was determined using a vmax229d ventilatory measurement system. the patients were asked to lift up pots weighing between 0.5 and 5.0 kg over a five-minute period, picking up the pots from a surface at waist level and putting them onto a shelf above head height. All the patients were evaluated regarding IC and using the Borg scale for dyspnea. the data were analyzed using Student's t test for paired samples, pearson's correlation and the wilcoxon test (p< 0.05). Results: there were reductions in IC and IC/tlC (p= 0.0001) following the ADl. the dyspnea increased after the exercise (p< 0.05). Conclusion: the ADl using the upper limbs caused Dh, as shown by the reductions in IC and IC/tlC and also by the increase in dyspnea.

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Flow-volume Curves and Breathing Patterns during Exercise in Patients with Obstructive Lung Disease

Cited by 55 publications

References 13 publications

Ventilatory mechanics and expiratory flow limitation during exercise in patients with obstructive lung disease

Ventilatory mechanics and expiratory flow limitation during exercise in patients with obstructive lung disease

Variability of within-breath reactance in COPD patients and its association with dyspnoea

Análise da hiperinsuflação pulmonar dinâmica (HD) após atividade de vida diária em pacientes com doença pulmonar obstrutiva crônica

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