Flow patterns in microfluidic system of CO2 + 1-propanol, ethanol, methanol, and hexane binary mixtures at high pressures

微小流路を利用した超臨界抽出プロセス

“…[supercritical extraction, phenolic acid, separation and purification, microfluidic system, slug flow] (1) CO 2 cylinder, (2) back pressure regulator, (3) cooler, (4) co-solvent tank, (5) pump, (6) CO 2 pre-heating coil, (7) solvent pre-heating coil, (8) swirl-mixer, (9) window T-junction, (10) light source, (11) digital microscope.…”

“…Symbols at 32°C (blue), 40°C (green), 50°C (black), 60°C (red) given in Table 1. (1) CO 2 cylinder, (2) silica filter, (3) cooling system, (4) co-solvent tank, (5) aqueous solution tank, (6) back pressure regulator, (7) pump, (8) pressure gauge, (9) safety valve, (10) preheating coil, (11) venting valve, (12) micro-mixing device, (13) temperature indicator, (14) extraction coil, (15) high pressure cell, (16) needle valve, (17) trapped CO 2 phase, (18) water bath, (19) dry gas flow meter.…”

LipTube: Liposome Formation in the Tube Process Using Supercritical CO2

“…64−67 The profits obtained from combining scCO 2 and flow processes were presented in our previous research, where micro-mixing and slug flow were utilized for the rapid extraction of phenolic compounds from an aqueous phase. 68 The micro-mixing device consists of four microchannels and enables continuous mixing of fluids in a limited space regardless of system pressure. Taking advantage of this device, Kawasaki et al successfully performed the continuous fabrication of NiO nanoparticles.…”