Flow-Injection Amperometric Determination of Tacrine based on Ion Transfer across a Water–Plasticized Polymeric Membrane Interface

Ortuño, J; Rueda, Carlos B.

doi:10.3390/s7071185

Cited by 6 publications

(4 citation statements)

References 23 publications

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“…The organic electrolyte salt was prepared by metathesis of bis(triphenylphosphoranylidene)ammonium chloride (BTPPACl) and potassium tetrakis(4chlorophenyl)borate (KTPBCl). The organic phase was mechanically stabilized as a polymer gel [38][39][40][41] and was composed of the supporting electrolyte (10 mM BTPPATPBCl) and low molecular weight poly(vinylchloride) (PVC) (10 % w/v), dissolved in 1,6-dichlorohexane. Prior to the experiments, both the aqueous and organic phase solvents were mutually pre-saturated.…”

Section: Reagentsmentioning

confidence: 99%

Electrochemical detection of ractopamine at arrays of micro-liquid | liquid interfaces

Sairi

Arrigan

2015

Talanta

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The behaviour of protonated ractopamine (RacH(+)) at an array of micro-interfaces between two immiscible electrolyte solutions (micro-ITIES) was investigated via cyclic voltammetry (CV) and linear sweep stripping voltammetry (LSSV). The micro-ITIES array was formed at silicon membranes containing 30 pores of radius 11.09±0.12 µm and pore centre-to-centre separation of 18.4±2.1 times the pore radius. CV shows that RacH(+) transferred across the water |1,6-dichlorohexane µITIES array at a very positive applied potential, close to the upper limit of the potential window. Nevertheless, CV was used in the estimation of some of the drug's thermodynamic parameters, such as the formal transfer potential and the Gibbs transfer energy. LSSV was implemented by pre-concentration of the drug, into the organic phase, followed by voltammetric detection, based on the back-transfer of RacH(+) from the organic to aqueous phase. Under optimised pre-concentration and detection conditions, a limit of detection of 0.1 µM was achieved. In addition, the impact of substances such as sugar, ascorbic acid, metal ions, amino acid and urea on RacH(+) detection was assessed. The detection of RacH(+) in artificial serum indicated that the presence of serum protein interferes in the detection signal, so that sample deproteinisation is required for feasible bioanalytical applications.

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Section: Reagentsmentioning

confidence: 99%

Electrochemical detection of ractopamine at arrays of micro-liquid | liquid interfaces

Sairi

Arrigan

2015

Talanta

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“…These interfaces can be used for understanding and developing practical electroanalytical processes and devices [9,32,36,563,564]. The electrochemical methods applied to liquid|liquid interfaces have proved a useful tool for the determination of ionic analytes not easily oxidized or reduced [36,45,119,121,136,141,149,153,254,273,336,496,562,[564][565][566][567][568][569][570][571][572][573][574][575][576][577][578][579][580].…”

Section: Practical Applicationsmentioning

confidence: 99%

Simple Ion Transfer at Liquid|Liquid Interfaces

Vallejo

Ovejero

Fernández

et al. 2012

International Journal of Electrochemistry

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The main aspects related to the charge transfer reactions occurring at the interface between two immiscible electrolyte solutions (ITIES) are described. The particular topics to be discussed involve simple ion transfer. Focus is given on theoretical approaches, numerical simulations, and experimental methodologies. Concerning the theoretical procedures, different computational simulations related to simple ion transfer are reviewed. The main conclusions drawn from the most accepted models are described and analyzed in regard to their relevance for explaining different aspects of ion transfer. We describe numerical simulations implementing different approaches for solving the differential equations associated with the mass transport and charge transfer. These numerical simulations are correlated with selected experimental results; their usefulness in designing new experiments is summarized. Finally, many practical applications can be envisaged regarding the determination of physicochemical properties, electroanalysis, drug lipophilicity, and phase-transfer catalysis.

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“…The flow-through cell incorporated the four electrodes and the membrane, which contained tetrabutylammonium tetraphenylborate. The determination of tetrabutylammonium was studied and two different amperometric methods, indirect and direct, were also developed for the determination of dodecylsulfate [ 212 ], tracine [ 213 ], tiapride [ 214 ], sulpiride [ 215 ] and catamphiphilic drugs such as the antiarrhythmic drugs procainamide and quinidine, the antimalarial quinine and the anesthetics bupivacaine, lidocaine, procaine and tetracaine [ 216 ]. Finally, a solvent polymeric membrane ion sensor has been applied to study the ion transfer of several ionic liquid cations, from water to a poly(vinyl chloride) membrane plasticized with 2-nitrophenyl octyl ether and the study has mainly been focused on dialkylimidazolium and alkylpyridinium cations [ 217 ].…”

Section: Electrochemical Sensorsmentioning

confidence: 99%

State-of-the-Art of (Bio)Chemical Sensor Developments in Analytical Spanish Groups

Plata

Contento

Ríos

2010

Sensors

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(Bio)chemical sensors are one of the most exciting fields in analytical chemistry today. The development of these analytical devices simplifies and miniaturizes the whole analytical process. Although the initial expectation of the massive incorporation of sensors in routine analytical work has been truncated to some extent, in many other cases analytical methods based on sensor technology have solved important analytical problems. Many research groups are working in this field world-wide, reporting interesting results so far. Modestly, Spanish researchers have contributed to these recent developments. In this review, we summarize the more representative achievements carried out for these groups. They cover a wide variety of sensors, including optical, electrochemical, piezoelectric or electro-mechanical devices, used for laboratory or field analyses. The capabilities to be used in different applied areas are also critically discussed.

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Flow-Injection Amperometric Determination of Tacrine based on Ion Transfer across a Water–Plasticized Polymeric Membrane Interface

Cited by 6 publications

References 23 publications

Electrochemical detection of ractopamine at arrays of micro-liquid | liquid interfaces

Electrochemical detection of ractopamine at arrays of micro-liquid | liquid interfaces

Simple Ion Transfer at Liquid|Liquid Interfaces

State-of-the-Art of (Bio)Chemical Sensor Developments in Analytical Spanish Groups

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