Florid Neovascularization of the Retina in a Diabetic Patient Undergoing Induction and Consolidation Therapy for Acute Promyelocytic Leukemia

Abstract

Acute promyelocytic leukemia treated with ATRA may result in upregulation of vascular endothelial growth factor in retinal tissues. Subsequent development of NVD may occur; however, this resolves well by cessation of ATRA and intravitreal injection of bevacizumab. We recommend that all patients undergoing treatment with ATRA for acute promyelocytic leukemia be monitored by an ophthalmologist.