Flora Paraibana: Annonaceae Juss

Pontes, Aline Fernandes; Barbosa, Maria Regina de Vasconcellos; Maas, P.J.M.

doi:10.1590/s0102-33062004000200008

Cited by 39 publications

(31 citation statements)

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“…From a phytochemistry point of view, this family is worth studying due to several types of structural compounds classes that can be found such as: alkaloids, amides, diterpenes, steroids, flavonoids and acetogenins (Pontes et al, 2004). The use of Annonaceae plants in folk medicine has been widely reported associated with varied biological activities such as antimicrobial, antiemetic, pesticide, abortive, antitumor, cytotoxic, anorexic and antimalarial (Leboeuf et al, 1982).…”

Section: In Vitro Cytotoxic Activity Of Brazilian Middle West Plant Ementioning

confidence: 99%

In vitro cytotoxic activity of Brazilian Middle West plant extracts

Mahmoud¹,

Marques²,

Pessoa³

et al. 2011

Rev. bras. farmacogn.

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Cytotoxic activity of eight plant extracts, native from the MidWest of Brazil comprising Cerrado, Pantanal and semideciduous forest, was evaluated for MDA-MB-435, SF-295, and HCT-8 cancer cell strains. A single 100 µg.mL -1 dose of each extract was employed with 72 h of incubation for all tests. Doxorubicin (1 µg.mL -1 ) was used as the positive control and the MTT method was used to detect the activity. Cytotoxicity of distinct polarities was observed in thirty extracts (46%), from different parts of the following species: Tabebuia heptaphylla (Vell.) Toledo, Bignoniaceae, Tapirira guianensis Aubl., Anacardiaceae, Myracrodruon urundeuva Allemão, Anacardiaceae, Schinus terebinthifolius Raddi, Anacardiaceae, Gomphrena elegans Mart., Amaranthaceae, Attalea phalerata Mart. ex Spreng., Arecaceae, Eugenia uniflora L., Myrtaceae, and Annona dioica A. St.-Hil., Annonaceae. Extracts of at least two tested cell strains were considered to be highly active since their inhibition rate was over 75%.

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Section: In Vitro Cytotoxic Activity Of Brazilian Middle West Plant Ementioning

confidence: 99%

In vitro cytotoxic activity of Brazilian Middle West plant extracts

Mahmoud¹,

Marques²,

Pessoa³

et al. 2011

Rev. bras. farmacogn.

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“…Annonaceae species are widely distributed around the world (Mello- Silva & Pontes, 2005) and are found in all the continents (Pontes et al, 2004); at a predominant way in tropical zones. This family of plants shows over 135 genera and 2500 species (Smith et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Chemical constituents of the volatile oil from leaves of Annona coriacea and in vitro antiprotozoal activity

Siqueira

Oliani

Sartoratto³

et al. 2011

Rev. bras. farmacogn.

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Abstract:The essential oil of the leaves from Annona coriacea Mart., Annonaceae, was extracted by hydrodistillation in a Clevenger apparatus and analyzed by GC/MS and GC/FID. The oil yield was 0.05% m/m. Sixty compounds were identified, in a complex mixture of sesquiterpenes (76.7%), monoterpenes (20.0%) and other constituents (3.3%). Bicyclogermacrene was its major compound (39.8%) followed by other sesquiterpenes. Most of the monoterpenes were in low concentration (<1%). Only β-pinene and pseudolimonene presented the highest level of 1.6%. The volatile oil presented anti-leishmanial and trypanocidal activity against promastigotes of four species of Leishmania and trypomastigotes of Trypanosoma cruzi, showing to be more active against Leishmania (L.) chagasi (IC50 39.93 µg/mL) (95% CI 28.00-56.95 µg/mL).

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“…The species A. dolichocarpa has a wide geographical distribution, being the neotropical species of Annonaceae most common and well distributed. In Brazil, it occurs in the states of Amapá, Amazonas, Acre, Rondônia, Goiás, Maranhão, Paraíba, Pernambuco, Bahia and Rio de Janeiro [6]. Chemical studies involving this species reported the isolation of two aporphinic alkaloids anaxagoreine and asimilobine [7] as well as volatile components of the essential oil extracted from the fruits [8,9].…”

Section: Introductionmentioning

confidence: 99%