1995
DOI: 10.1001/archotol.1995.01890030020004
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Floor of Mouth Carcinoma: The Management of the Clinically Negative Neck

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Cited by 136 publications

(101 citation statements)
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“…The rate of pathological cervical node involvement in those undergoing elective neck dissection was 36.8%, which is similar to the 38.5% rate of regional recurrence in the observation group supporting the notion that these groups are comparable with regard to disease biology. Although this is in keeping with the literature,6–10 the figure is higher than we expected for T1 to T2 disease but most likely reflects the exclusion of thin tumors. Tumor thickness appears to be a critical factor in the beneficial effect of elective neck dissection.…”
Section: Discussionsupporting
confidence: 91%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The rate of pathological cervical node involvement in those undergoing elective neck dissection was 36.8%, which is similar to the 38.5% rate of regional recurrence in the observation group supporting the notion that these groups are comparable with regard to disease biology. Although this is in keeping with the literature,6–10 the figure is higher than we expected for T1 to T2 disease but most likely reflects the exclusion of thin tumors. Tumor thickness appears to be a critical factor in the beneficial effect of elective neck dissection.…”
Section: Discussionsupporting
confidence: 91%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Although elective treatment of occult neck disease remains controversial, several investigators have emphasized increased survival in patients undergoing elective neck dissection compared with the “wait and see” approach. 5 The incidence of occult lymph node metastasis detected by SND was 23% in the present study. Among those occult diseases, 32% harbored more than one metastatic node and 24% had extracapsular spread.…”
Section: Discussionsupporting
confidence: 49%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…In the literature, the reported salvage rate varies from as low as 27% to 82% (average, 50%) after a regional recurrence (Table 2). [11][12][13][14][15][16][17] In this study we found a salvage rate of 71%, although our follow-up period is still limited. As the prognosis is closely related to the metastatic burden in the neck as well as to the presence of extranodal spread, the delay between the treatment of the primary tumor and the neck is probably crucial.…”
Section: Methodsmentioning
confidence: 53%
“…The failure rate in the neck of 18% compares favorably with the incidence of occult metastases quoted in the literature for patients treated with transoral tumor excision and a wait-and-see policy for the neck [11][12][13][14][15][16][17]…”
Section: Commentmentioning
confidence: 65%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.