Flexible monitoring system for automated detection of bacterial growth in a commercial specimen processing platform

Bellitti, Paolo; Bona, Michele; Borghetti, Michela; Sardini, Emilio; Serpelloni, Mauro

doi:10.1109/rtsi.2017.8065950

Cited by 4 publications

(5 citation statements)

References 12 publications

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“…We found an accuracy of 0.8 % by comparing its response with the values measured by a reference instrument (i.e. the HP4194A impedance analyser) for the same device under test [26]. This is comparable with the value provided by the AD5933 datasheet [28].…”

Section: The Performed Testssupporting

confidence: 72%

“…Although we used a laptop in this work to augment system portability, any computer that is able to run the VI can be potentially employed for the proposed measuring system. This VI is a more advanced version than the one previous characterising system prototype illustrated in [26]. In particular, we added some features that increase measuring system connectivity with collaborating devices, following an architecture that is compliant with Industry 4.0 paradigms.…”

Section: Laptopmentioning

confidence: 99%

“…Compared to the previous versions illustrated in [25]- [26] in which connectivity was not an addressed issue, the solutions implemented by the measuring system proposed in this paper promote information exchange between the actors that play a role in the analytical process, as presented in Figure 4. This exchange is beneficial.…”

Section: Connectivitymentioning

confidence: 99%

“…Therefore, it presents a case study about the application of Industry 4.0 principles to microbiology. At the same time, this article proposes an improved system compared with previous versions illustrated in other works [25]- [26], regarding both electronics and user interface development.…”

Section: Introductionmentioning

confidence: 99%

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Reconfigurable measuring system for the automatic detection of bacterial growth in a specimen processing platform

et al. 2019

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The detection of bacterial infections in biological samples represents a fundamental task in human health preservation. This paper describes a measuring system that aims to detect bacterial growth in Petri dishes while they are inside the incubator of the WASPLab® specimen processing platform (COPAN Italia S.p.A.). In fact, the interaction between the system and the WASPLab® enhances the analytical process. The proposed system monitors bacterial growth by measuring the impedance related to the examined Petri dishes. Furthermore, it can be easily reconfigured according to user requirements. Finally, it has some features that enhance its connectivity with the WASPLab® and other devices, developing a structure that is compliant with the Industry 4.0 model. We assess the system performance through different tests, in which we monitored the growth of S. aureus ATCC 6538, starting from concentrations in the order of 4.5.108 CFU/ml, 4.5.107 CFU/ml, and 4.5.106 CFU/ml. The results show the system’s correct operation both in an ad hoc setup and while working with the WASPLab®. Furthermore, the connectivity between the system and other devices allows for a user to be informed about the analyses that are on course and to act on the system at any time and even from remote locations.

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Section: The Performed Testssupporting

confidence: 72%

Section: Laptopmentioning

confidence: 99%

Section: Connectivitymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Reconfigurable measuring system for the automatic detection of bacterial growth in a specimen processing platform

et al. 2019

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“…Bacterial infections represent a serious threat to human and one of the leading causes of death globally (Bellitti et al , 2017; Sheybani and Shukla, 2016). Such infections can be water-borne, food-borne, air-borne and environmentally borne or originate from surgical interventions, which were not completely sterile.…”

Section: Introductionmentioning

confidence: 99%

Comparison of performances of flexible sensors on foil and paper for efficient bacterial concentration measurement

Kojić

Radovanović

Stojanović

et al. 2020

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Purpose The purpose of this study was to develop flexible sensors for detection of different concentrations of bacteria, such as Pseudomonas aeruginosa and Staphylococcus aureus, in saline. Design/methodology/approach The sensors were fabricated using ink-jet printing technology and they consist of a pair of silver interdigitated electrodes printed on mechanically flexible substrates – foil and paper. In house measurement setup for testing and characterization of sensors has been developed. Structural, electrical and mechanical properties of flexible sensors have been determined and compared. Findings The characteristics of sensor – the resonant frequency as a function of different concentrations of each bacteria – are presented. The obtained results demonstrate different resonant frequencies for each dilution of Pseudomonas aeruginosa and Staphylococcus aureus in physiological saline. Research limitations/implications Both sensors showed accurate measurements of bacterial count, which can be achieved with detection of resonant frequency, and this is reflective of the number of bacterial cells within a sample. Practical implications The findings suggest that the newly developed method based on measuring resonant frequency corresponds well with bacterial cell count, thus establishing a new proof-of-concept that such method can have significant applications in bacterial cell counting that are economic and easily maintained. Social implications Fast, cost-effective, accurate and non-invasive method for detection of different bacteria from saline was developed. Originality/value For the first time, comparison between performances of flexible sensors on foil and paper for bacteria detection is demonstrated. Almost linear dependence between shift of resonant frequency of developed sensors and concentration of bacteria has been obtained.

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Study Toward the Integration of a System for Bacterial Growth Monitoring in an Automated Specimen Processing Platform

Bellitti

Bona

Fontana³

et al. 2019

Lecture Notes in Electrical Engineering

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Flexible monitoring system for automated detection of bacterial growth in a commercial specimen processing platform

Cited by 4 publications

References 12 publications

Reconfigurable measuring system for the automatic detection of bacterial growth in a specimen processing platform

Reconfigurable measuring system for the automatic detection of bacterial growth in a specimen processing platform

Comparison of performances of flexible sensors on foil and paper for efficient bacterial concentration measurement

Study Toward the Integration of a System for Bacterial Growth Monitoring in an Automated Specimen Processing Platform

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