Flexible hydrogel non-enzymatic QCM sensor for continuous glucose monitoring

Research progress of electrode materials for non-enzymatic glucose electrochemical sensors

“…Therefore, boric acid can be used as a recognition site for saccharide sensors in the field of glucose detection. Liu et al 68 presented a continuous glucose monitoring platform consisting of a quartz crystal microbalance (QCM) quartz and a flexible hydrogel recognition system. A stretchable hydrogel is employed as the support material and antifouling membrane, and glucose-sensitive monomer phenylboronic acid (PBA) is employed as the recognition part.…”

Ti3C2Tx MXene as Electrocatalyst for Designing Robust Glucose Biosensors

“…[147,148] Because CGM sensors operate in biological tissues, they are easily influenced by the presence of certain active chemicals in the interstitial fluid. [149] Strategies need to be developed to avoid interference, stabilize the GOx enzyme, immobilize certain mediators with the GOx enzyme, and, most critically, to identify biosafe and biocompatible nanomaterials that can replace GOx. [150,151] MXene-based CGM has received little attention to date.…”

One-Dimensional Responsive Photonic Crystals Assembled by Polymer Nanogels and TiO2 Nanoparticles for Rapid Detection of Glucose

“…In early researches, various analytical instruments or technologies have been developed, such as near-infrared diffuse reflectance spectroscopy, 2 surface plasmon resonance, 3 Raman spectroscopy, 4 and quartz crystal microbalance. 5 However, expensive costs and complex operational procedures of these instruments restrict practical applications. Consequently, various chemical substances that could bind with 1, 2-cis-diol groups of glucose in solution were reported, including glucose oxidase (GOx), 6,7 concanavalin A (Con A), 8−10 and phenylboronic acid (PBA), 11−15 and some chemical sensors based on these substances have been reported, such as fluorescence sensors, 16−20 electrochemical sensors, 21−25 gels, 26−29 and photonic crystals.…”