Flexible direct-growth CNT biosensors

Chang, Yun-Tzu; Huang, Jing-Huei; Tu, Meng-Che; Chang, Po‐Cheng; Yew, Tri‐Rung

doi:10.1016/j.bios.2012.09.049

Cited by 35 publications

(12 citation statements)

References 27 publications

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“…Their characteristics and performance are significantly affected by the fabrication techniques and distribution. A biosensor was fabricated by growing CNTs directly on a flexible polyimide substrate at low temperatures and used to quantitatively detect human serum albumin (HSA) via impedance spectroscopy (Chang et al 2013).…”

Section: Carbon-based Nanomaterials-graphene and Carbon Nanotubes (Cnmentioning

confidence: 99%

“…Through various processing techniques such as chemical vapor deposition (Bhattacharyya et al 2011), suspension coating (Xu and Wang 2009), stamping (Wang et al 2010), drop casting (Segev-Bar et al 2013), self-assembly (Choi et al 2010), electrodeposition , inkjet printing (Xiang et al 2016;Zahra et al 2014), screen printing (Chou et al 2014;Du et al 2016), nanoparticles (Wang et al 2010;Xu and Wang 2009;Zan et al 2013) or one-dimensional nanostructures like nanotubes (Chang et al 2013;Juntae et al 2008), nanowires (Convertino et al 2016), and nanorods (Chen et al 2015) can be formed into thin films or sensing arrays which are used to decorate surfaces, or integrate in substrates to achieve improved performance. A pen-on-paper approach could also be used to deposit different types of nanomaterials (Au nanospheres, Au nanorods, and Ag nanospheres) (Polavarapu et al 2014).…”

Section: Fabrication Strategiesmentioning

confidence: 99%

See 1 more Smart Citation

The design, fabrication, and applications of flexible biosensing devices

Meng

Obodo

Yadavalli

2019

Biosensors and Bioelectronics

144

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Flexible biosensors form part of a rapidly growing research field that take advantage of a multidisciplinary approach involving materials, fabrication and design strategies to be able to function at biological interfaces that may be soft, intrinsically curvy, irregular, or elastic. Numerous exciting advancements are being proposed and developed each year towards applications in healthcare, fundamental biomedical research, food safety and environmental monitoring. In order to place these developments in perspective, this review is intended to present an overview on field of flexible biosensor development. We endeavor to show how this subset of the broader field of flexible and wearable devices presents unique characteristics inherent in their design. Initially, a discussion on the structure of flexible biosensors is presented to address the critical issues specific to their design. We then summarize the different materials as substrates that can resist mechanical deformation while retaining their function of the bioreceptors and active elements. Several examples of flexible biosensors are presented based on the different environments in which they may be deployed or on the basis of targeted biological analytes. Challenges and future perspectives pertinent to the current and future stages of development are presented. Through these summaries and discussion, this review is expected to provide insights towards a systematic and fundamental understanding for the fabrication and utilization of flexible biosensors, as well as inspire and improve designs for smart and effective devices in the future.

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Section: Carbon-based Nanomaterials-graphene and Carbon Nanotubes (Cnmentioning

confidence: 99%

Section: Fabrication Strategiesmentioning

confidence: 99%

The design, fabrication, and applications of flexible biosensing devices

Meng

Obodo

Yadavalli

2019

Biosensors and Bioelectronics

144

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“…Chang et al used a biocompatible polymer poly(p-xylylene) (parylene) to coat CNTs grown on a poly(imide) substrate. 97 The insulating coating permitted this flexible biosensor to be suitable for human serum albumin detection (3  10 -11 mg/ml) in vivo. Stable glutamate dehydrogenase (GDH) biosensors crosslinked with PEI were produced by Garcia-Galan et al 98 Biotechnological uses for this enzyme have been unreported to date, owing to their poor stability.…”

Section: Biosensorsmentioning

confidence: 99%

Polymer coatings for biomedical applications: a review

Smith

Lamprou

2014

Transactions of the IMF

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This review surveys some of the recent literature concerning the use of polymer coatings for a variety of biomedical applications. These have been grouped into six broad categories: orthopaedic materials, cardiovascular stents, antibacterial surfaces, drug delivery, tissue engineering and biosensors. These, to some extent overlapping, sections have been ordered such that the literature generally progresses from polymer coatings on metallic to non-metallic substrates. Polymer coatings can bestow a wide-range of functionalities due to their various properties, such as anti-wear and characteristics, mechanical strength, corrosion protection, electrical conductivity, biocompatibility and surface chemistry. The review period is from 2011 to the present (2013).

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“…Similarly, Chang et al 80 have demonstrated the feasibility of CNT exible biosensors by observing a change in the EDL capacitance, C dl , for the detection of human serum albumin (HSA)-which is frequently used to monitor liver function. The utilization of carbon nanotubes (CNTs) can be attributed to their high surface-to-volume ratio, excellent electrical conductivity, and mechanical strength, which are benecial for obtaining highly sensitive nanosensors.…”

Section: Electrochemical Impedance Spectrotroscopy (Eis)mentioning

confidence: 99%