Flavonoids from Blumea balsamifera

Ali, Dafaalla Mohamed Hag; Wong, K. C.; Lim, Phaik-Leng

doi:10.1016/j.fitote.2004.10.015

Cited by 29 publications

(21 citation statements)

References 4 publications

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“…Several studies on the chemical constituents of B. balsamifera DC have been reported and a number of flavanoids have been isolated from this plant. The essential oil of B. balsamifera contains l-borneol, cineole, limonene, and palmitic and myristic acid, sesquiterpene alcohol, dimethyl ether, pyrocatechic tannin, glycoside, and levorotatory camphor (Ruangrungsi et al, 1981;Barua and Sharma, 1992;Fazilatun et al, 2001Fazilatun et al, , 2004Ali et al, 2005). Additionally, the flavonoids present in B. balsamifera DC leaves extracts are potent antioxidants (Fazilatun et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Cloning and sequence analysis of the Blumea balsamifera DC farnesyl diphosphate synthase gene

Pang¹,

Guan²,

Wu³

et al. 2014

Genet. Mol. Res.

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ABSTRACT. Blumea balsamifera DC is a member of the Compositae family and is frequently used as traditional Chinese medicine. Blumea balsamifera is rich in monoterpenes, which possess a variety of pharmacological activities, such as antioxidant, anti-bacteria, and antiviral activities. Farnesyl diphosphate synthase (FPS) is a key enzyme in the biosynthetic pathway of terpenes, playing an important regulatory role in plant growth, such as resistance and secondary metabolism. Based on the conserved oligo amino acid residues of published FPS genes from other higher plant species, a cDNA sequence, designated BbFPS, was isolated from B. balsamifera DC using polymerase chain reaction. The clones were an average of 1.6 kb and contained an open reading frame that predicted a polypeptide of 342 amino acids with 89.07% identity to FPS from other plants. The deduced amino acid sequence was dominated by hydrophobic regions and contained 2 highly conserved DDxxD motifs that are essential for proper functioning of FPS. Phylogenetic analysis indicated that FPS grouped with other Blumea balsamifera DC farnesyl diphosphate synthase composite families. Prediction of secondary structure and subcellular localization suggested that alpha helices made up 70% of the amino acids of the sequence.

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Section: Introductionmentioning

confidence: 99%

Cloning and sequence analysis of the Blumea balsamifera DC farnesyl diphosphate synthase gene

Pang¹,

Guan²,

Wu³

et al. 2014

Genet. Mol. Res.

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“…Biological activity of B. balsamifera has been reported previously, such as wound healing activity of the essential oil from the leaves, anti hyperglycemic activity of the residues fraction and free-radical scavenging activity of the leaves extract [11][12][13]. Some flavonoids had been isolated from the leaves extract of the plant [14]. To the best of our knowledge, the antimicrobial activity against C. albicans of the plant extract has not been reported.…”

Section: Resultsmentioning

confidence: 92%

Anticandidal activity of several plants used by Bentian tribe in East Kalimantan, Indonesia

Kusuma¹,

Sari²,

Murdiyanto³

et al. 2016

AIP Conference Proceedings

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“…Various fl avonoids have been isolated from the leaves and these fl avonoids responsible for antioxidant activity, ACE inhibitory activity, anti-infl ammatory activity and sudorifi c properties (4, 2, 3). Previous studied by Ali et al (2005) reported that new constituents of fl avonoids 3,4,5-trihydroxy-3,7-dimethoxyflavanone,3,4,5trihydroxy-7-ethoxyfl avanone and new bifl avonoid, 3-O-7-biluteolin have been successfully isolated from sembung leaves using soxhlet extraction methods (4).…”

Section: Introductionmentioning

confidence: 99%

Effect of loloh sembung (Blumea balsamifera) maturity stage on antioxidant activity

Kusumawati

Reyunika

Yogeswara

et al. 2019

IJND

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ABSTRAKLatar belakang: Loloh sembung (Blumea balsamifera) adalah minuman tradisional masyarakat Bali yang digunakan untuk mengobati penyakit. Perbedaan kematangan daun sembung akan mempengaruhi aktivitas antioksidan loloh sembung. Tujuan: Penelitian ini bertujuan untuk menentukan aktivitas antioksidan loloh sembung yang dibuat dari berbagai jenis kematangan daun sembung yang diekstrak dengan menggunakan pelarut air. Metode: Serbuk daun sembung pada tingkat kematangan yang berbeda (muda, dewasa dan tua) direbus untuk menghasilkan loloh sembung. Analisis kandungan antioksidan meliputi analisis total fenolik, total kandungan fl avonoid dan aktivitas antioksidan ferric reducing antioxidant power (FRAP). Hasil: Hasil analisis menunjukkan bahwa daun sembung dengan tingkat kematangan tua menunjukkan kandungan total fenolik dan aktivitas antioksidan yang tinggi dibandingkan dengan daun dewasa dan muda, yaitu masing-masing sebesar 0,85 ±0,005 GAE/g dan 0,66 ±0,003 mmol Fe 2+ /g sampel. Sedangkan, daun dengan tingkat kematangan dewasa menunjukkan total fl avonoid yang tinggi, yaitu sebesar 0,39±0,006 QE/g. Berdasarkan korelasi Pearson, perbedaan tingkat kematangan daun menunjukkan korelasi positif dengan kandungan total fenolik, total fl avonoid dan aktivitas antioksidan (FRAP). Kesimpulan: Perbedaan tingkat kematangan daun sembung menunjukkan korelasi positif dengan kandungan total fenolik, total fl avonoid dan aktivitas antioksidan (FRAP). Penelitian ini menunjukkan bahwa loloh sembung berpotensi sebagai minuman fungsional yang memanfaatkan kearifan lokal. ABSTRACT Background: A Loloh sembung (Blumea balsamifera) is a traditional herbal drink from Bali and widely used to treat several diseases by Balinese people. Sembung leaf at different maturity stages would affect antioxidant activity of loloh sembung.Objectives: The objective of the research was determined antioxidant activity of loloh sembung prepare from different maturity stages of sembung leaf and extracted using water. Methods: Sembung leaves powder at different maturity stages (young, mature and old) was boiled to produce loloh sembung. The analyses of antioxidant activity of loloh sembung included total phenolic content (TPC), total fl avonoid content (TFC) and ferric reducing antioxidant power (FRAP). Results: The results showed that old leaves were signifi cantly higher in TPC and FRAP values compare to mature and young leaves, i.e 0.8575±0.005 GAE/g and 0.6625±0.003 mmol Fe 2+ /g sample respectively. However, the mature leaves revealed signifi cantly high TFC, i.e 0.3972±0.006 QE/g. Based on Pearson's correlation coeffi cient, the difference of maturity stage exhibited positive correlation with TPC, TFC and FRAP.

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Flavonoids from Blumea balsamifera

Cited by 29 publications

References 4 publications

Cloning and sequence analysis of the Blumea balsamifera DC farnesyl diphosphate synthase gene

Cloning and sequence analysis of the Blumea balsamifera DC farnesyl diphosphate synthase gene

Anticandidal activity of several plants used by Bentian tribe in East Kalimantan, Indonesia

Effect of loloh sembung (Blumea balsamifera) maturity stage on antioxidant activity

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